Biorepository: Vaccine and Infectious Disease

COVID-19, vaccines and more

What Is the Vaccine and Infectious Diseases Biorepository?

The Vaccine and Infectious Diseases Biorepository is a confidential list of people who are willing to participate in a vaccine study, have had a virus, or who have lived in a dengue virus risk area. This biorepository played a key role in much of BRI’s COVID-19 research, helping scientists answer key questions about the virus at the height of the pandemic.

Our team uses donated samples and personal and family health information to better understand the causes and long-term health effects of infectious diseases, as well as how to improve vaccines and disease prevention. All information is kept confidential, and samples and health information are coded with numbers, not names.

Participate in Vaccine and Infectious Disease Research

We are currently looking for adults, age 18 and older, who do not have a history of immune-mediated disease and who:

  • Had or currently have a viral infection.
  • Are planning on getting a vaccine or have already received one.
  • Have lived in a dengue virus risk area for 10 or more years, such as India, Indonesia, Vietnam, Thailand, the Philippines, Sri Lanka or Singapore, among others.

We are currently leading studies on the following:

Vaccine studies Virus infection studies Other infectious disease studies
  • Yellow fever vaccine
  • Japanese encephalitis vaccine
  • Influenza (flu) vaccine
  • H1N1 vaccine
  • Seasonal flu and H1N1 combination vaccine
  • West Nile virus
  • Dengue virus
  • Influenza A
  • Rhinovirus
  • Aspergillosis
  • Clostridium difficile (C. diff.)
  • Others

We are also looking for people of all ages who do not have an immune-mediated or autoimmune disease to join our Healthy Volunteer Biorepository.

Learn more about infectious diseases

Join the vaccine and infectious disease biorepository

Consider donating to our biorepository to help advance research.
Uma Malhotra
Affiliate Investigator

Uma Malhotra, MD

Affiliate Investigator
View Full Bio
By the Numbers

702+

Participants

27,004+

Samples

What Infectious Disease Research Is BRI Conducting?

  • Better understanding how the immune system responds to bacterial, fungal and viral infections
  • Exploring and improving diagnostics, treatment and prevention of many infections including influenza (flu), dengue fever, yellow fever, Japanese encephalitis, West Nile virus, aspergillosis and many other infectious diseases.
  • Exploring how to better tailor COVID-19 treatments and prevention to different populations
  • Understanding if and how viruses trigger autoimmune diseases

Learn more about COVID-19 and infectious diseases.

Labs Studying Infectious Diseases

Bolouri Lab Main

Bolouri Lab

The Bolouri lab is interested in developing and applying computational systems immunology methods to better understand dysregulated immune cell development and differentiation.
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Campbell Lab Main

Campbell Lab

The Campbell laboratory is interested in understanding the basis for T cell activation, function and tolerance.
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Hamerman Lab Main

Hamerman Lab

The lab is interested in understanding how myeloid cells contribute to both productive and pathological immune responses during infection, inflammation, and autoimmune diseases.
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Lacy-Hulbert Res Proj Main - Forward Genetics

Lacy-Hulbert Lab

The Lacy-Hulbert lab works to understand how different aspects of the immune system cooperate to identify and combat potentially infectious organisms while preventing immune attack against innocuous microbes or the body’s own self.
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Speake Research Project Main - TrialNet Pathway to Prevention

Speake Lab

The Speake group is interested in advancing clinical research – especially in type 1 diabetes, but also in the context of other immune-mediated diseases.
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Stefani Lab Main

Stefani Lab

The goal of our research is to better understand mechanisms of sensing and repair during diseases like cancer, infections, and neurodegenerative disorders.
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Ziegler Lab Main

Ziegler Lab

The Ziegler laboratory is investigating the role of the epithelial cytokines TSLP and IL-33 in regulating protective responses at mucosal barrier surfaces such as the respiratory and gastrointestinal tracts.
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Blog Stories

Blog Main Image - Researcher Woman Examining Samples Blue
January 10, 2024

On the Brink of a Golden Age of Medicine

"I know we will reach that golden age, and BRI’s research in human immunology is the vehi¬cle that will take us there. This field has shepherded incredible advances in recent years, including new vaccines, new cancer treatments, and new and better treatment options for autoimmune disease."
Read Article
Blog Main Image - Man Coding Single Screen
June 30, 2023

Big Data Reveals Surprising Defense Against COVID-19

“If you’d asked me in March 2020, I’d have said the pandemic was going to be really bad for my asthma patients. But we saw the opposite,” says Matt Altman, MD, MPhil, who treats patients with allergies and asthma at UW Medicine and conducts research at BRI.
Read Article
Dr. Buckner reviewing information
February 4, 2023

BRI's Vision of Immune Health

A message from BRI President Jane Buckner, MD, about BRI's new, broader vision for immune health.
Read Article

Immuno-what? Hear the latest from BRI

Keep up to date on our latest research, new clinical trials and exciting publications.