New Study Finds Germinal Centers Are Regulated by TSLP in B and T Cells
BRI scientists have shown that thymic stromal lymphopoietin (TSLP) signaling regulates germinal center (GC) function. During an infection, GCs form in lymphoid tissues such as the lymph nodes, tonsils and spleen. Their activity results in long-lived and high-affinity antibodies, which provide long-term immunity against infection. These findings will impact future research on autoimmune among other diseases. More