Scientists at BRI, led by Erik Wambre, PhD, made the breakthrough discovery that could change allergy research worldwide, by identifying a single type of cell that appears to drive all allergies.

As Wambre and his colleagues analyzed the blood samples from BRI’s Allergy and Asthma Biorepositories, they discovered a specialized subtype of cell, which they called Th2A, which is present in people with allergies but almost entirely absent from people who don’t have allergies.

This cell, called Th2A, could be a promising focal point for future research to improve diagnosis, monitoring and treatment of allergies. Additionally, the cell could be used as an indicator to show whether a person has an allergy or is responding to therapy.

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