Highlights

New Study Identifies Novel Mechanism of Tregs’ Role in Maintaining Immune System Homeostasis

Tregs prevent the immune system from overreacting to harmless substances and from reacting to the body’s own cells, which leads to autoimmunity. The molecular changes that Tregs induce to suppress the immune response have previously remained unclear. These new results show that when Tregs interact with CD4 effector T cells (Teffs), the cells that promote an inflammatory response, they suppress protein synthesis, preventing cell division and the production of more Teffs. More

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