Autoimmune Life Blog

In the late 1990s, Bill Kwok, PhD, pioneered MHC class II tetramers, a game-changing tool in immunology research. Tetramers have fueled countless research breakthroughs because they enable scientists to find extremely rare cells and extract them to study in precise detail.

Eddie James, PhD, earned a new grant to explore early cell changes that lead to T1D, using a new tool pioneered at BRI.

Sarah Kobernat, PhD, is working to find out.

Learn how our biorepositories power life-changing breakthroughs.

Benaroya Research Institute honors and remembers (“Becky”) Benaroya, a beloved member of our community whose generosity, compassion and commitment to improving lives leaves a remarkable impact.

Learn how research led by Jane Buckner, MD, is bringing regulatory T cell-based therapies closer to clinical trials.

Allyson Byrd, PhD, is an expert in the gut microbiome, the study of the tiny organisms that live inside our digestive system. James Lord, MD, PhD, is a gastroenterologist who has studied inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis for more than 20 years.

Learn how CRISPR-Cas9-based genome engineering using adeno-associated virus (AAV) vectors is helping BRI scientists make breakthroughs to study human T cells and explore new treatments for type 1 diabetes, as well as  develop preclinical models to study T cells and B cell

At first, Cate Speake, PhD, and her team weren’t sure that a mysterious phenomenon called autoantibody reversion was actually happening. But no matter how they sliced the data, they saw the same pattern. Learn how autoantibody reversion could unlock new clues to preventing type 1 diabetes.

Learn how lab-grown human beta cells are helping Eddie James, PhD, and other BRI researchers answer important questions in type 1 diabetes.