Your gifts fuel groundbreaking discoveries and life-changing care.
BRI is a world leader in human immunology. We’re taking on some of the most challenging questions in our field, aiming to improve the lives of people with immune system diseases like autoimmune diseases, cancer, asthma and allergies. Thanks to the incredible support of our donor community, we're making progress on better treatments — and moving closer to prevention and cures.
Last March, BRI Advisory Board member Gretchen Schoenstein ran two half-marathons in two days on two coasts to rally people around Autoimmune Disease Awareness Month and to raise funds for BRI’s Innovation Fund.
Why BRI
“Meeting BRI’s team showed us that BRI gets it — they know there’s a lot of work to do, but they’re innovative and persistent. It showed us, without a doubt, BRI will be the ones to find a cure.”
- BRI supporter Gretchen Schoenstein
Immune system diseases by the numbers
1 in 15
Americans have an autoimmune disease
110+
Known autoimmune diseases
2
Children in every classroom have a severe allergy
Philanthropy in Action at BRI
“A transformational gift from one of BRI’s generous donors helped get my lab off the ground. That gift paved the way for discoveries that are helping us better understand the cells and processes that lead to lupus and other autoimmune diseases.”
BRI Scientist Jessica Hamerman, PhD
May 7, 2025
Autoantibody Reversion: A Mystery That Could Help Prevent T1D
At first, Cate Speake, PhD, and her team weren’t sure that a mysterious phenomenon called autoantibody reversion was actually happening. But no matter how they sliced the data, they saw the same pattern. Learn how autoantibody reversion could unlock new clues to preventing type 1 diabetes.
October 23, 2024
Innovation Fund Spotlight: Single-Cell CRISPR Screening To Explore Genetics and Autoimmune Diseases
Together, Jessica Hamerman, PhD, and John Ray, PhD, are exploring the genetic roots of autoimmune disease using single-cell CRISPR screening.
October 23, 2024
Innovation Fund Spotlight: Lab-Grown Beta Cells Meet State-Of-The-Art Imaging To Answer New Questions About Type 1 Diabetes
BRI investigators Eddie James, PhD, and Caroline Stefani, PhD, are teaming up to take a unique approach to type 1 diabetes research.
