Center for Systems Immunology
With the explosion of data from genome studies and molecular profiling technologies, huge amounts of biological information are now available. Scientists in this Center use complex systems theory and high throughput techniques as well as mathematical and computational tools to understand the functioning of the immune system in health and disease.
Leadership
Peter S. Linsley, PhD | Charlie Quinn |
Bioinformatics Group
The BRI Bioinformatics Group comprises computational biologists and biostatisticians, with access to a high-performance computing infrastructure and specialized software to support processing, analyzing and visualizing data from heterogeneous sources, including BRI and Virginia Mason laboratories. |
Data Management & Software Development Group
Our Data Management & Software Development Group has created an extensive data infrastructure to provide our scientists with flexible acquisition and query-based access to ever increasing amounts of research data. Our systems are designed to link with advanced bioinformatics analysis tools, where the co-location of data and scalable computational power is sometimes advantageous. Included in our system are a collection of secure web-based applications:
We are committed to free distribution of our datasets, and code. Upon publication, we deposit supporting data files into public repositories like Immport and GEO. In many cases we share our application and analysis code via GitHub. |
Core Laboratories
Genomics Core |
Research Laboratories
Linsley Laboratory Presnell & Altman Laboratory Bolouri Laboratory Ray Laboratory Mandelson Laboratory |