Faculty & Scientific Staff
Karen Cerosaletti, PhD
Director, Center for Translational Immunology; Associate Member; Principal Investigator, Cerosaletti Lab
206.287.5623
Background Information
Dr. Cerosaletti received a bachelor’s degree in Biology from the College of Saint Rose in Albany, New York. She worked in infectious disease research before obtaining her PhD in Immunology from the University of Rochester in 1990. After post-doctoral work in somatic cell genetics in the Molecular Medicine Program at Fred Hutchinson Cancer Research Center in Seattle, she joined Benaroya Research Institute (BRI) in 1995. She is currently Director of the Center for Translational Immunology, Manager of the Genotyping Core, and an Associate Member at BRI.
Featured Publications
Sep 2023
Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.
Commun Biol
Newman JRB, Long SA, Speake C, Greenbaum CJ, Cerosaletti K, Rich SS, Onengut-Gumuscu S, McIntyre LM, Buckner JH, Concannon P
Sep 2023
Proinflammatory islet antigen reactive CD4 T cells are linked with response to alefacept in type 1 diabetes.
JCI Insight
Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K
Mar 2023
PTPN22 R620W gene editing in T cells enhances low avidity TCR responses.
Elife
Anderson W, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Buckner JH, Rawlings DJ
Oct 2022
Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
Sci Transl Med
Yang SJ, Singh AK, Drow T, Tappen T, Honaker Y, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Mauk K, Xiang Y, Smith J, Mortensen E, Cook PJ, Sommer K, Khan I, Liggitt D, Rawlings DJ, Buckner JH
Jul 2022
IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation.
Front Immunol
Lambert K, Diggins KE, Jones BE, Hundhausen C, Maerz MD, Hocking AM, Sanda S, Greenbaum CJ, Linsley PS, Cerosaletti K, Buckner JH
