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From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL-33.
Clin Transl ImmunologyObata-Ninomiya K, Jayaraman T, Ziegler SF -
Antigen-specific immunotherapies for autoimmune disease.
Nat Rev RheumatolBuckner JH -
Urinary proteomics identifies distinct immunological profiles of sepsis associated AKI sub-phenotypes.
Crit CareStanaway IB, Morrell ED, Mabrey FL, Sathe NA, Bailey Z, Speckmaier S, Lo J, Zelnick LR, Himmelfarb J, Mikacenic C, Evans L, Wurfel MM, Bhatraju PK -
Efficacy and Safety of Dupilumab in Children With Peanut Allergy: A Multicenter, Open-Label, Phase II Study.
AllergySindher SB, Nadeau KC, Chinthrajah RS, Leflein JG, Bégin P, Ohayon JA, Ponda P, Wambre E, Liu J, Khokhar FA, Akinlade B, Maloney J, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel N, Patel K, Laws E, Mannent LP, Radin AR -
Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy.
AllergyChinthrajah RS, Sindher SB, Nadeau KC, Leflein JG, Spergel JM, Petroni DH, Jones SM, Casale TB, Wang J, Carr WW, Shreffler WG, Wood RA, Wambre E, Liu J, Akinlade B, Atanasio A, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel K, Laws E, Mannent LP, Adelman DC, Ratnayake A, Radin AR -
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
bioRxivMaguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, IMPACC Network, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E -
Cytokine signatures in post-endoscopic retrograde cholangiopancreatography pancreatitis: a pilot study.
Ann GastroenterolMachicado JD, Lee PJ, Culp S, Stello K, Hart PA, Ramsey M, Lacy-Hulbert A, Speake C, Cruz-Monserrate Z, Elmunzer BJ, Whitcomb DC, Papachristou GI -
High-dose Intravenous BCG Vaccination Induces Enhanced Immune Signaling in the Airways
Sci AdvPeters JM, Irvine EB, Makatsa MS, Rosenberg JM, Wadsworth MH 2nd, Hughes TK, Sutton MS, Nyquist SK, Bromley JD, Mondal R, Roederer M, Seder RA, Darrah PA, Alter G, Seshadri C, Flynn JL, Shalek AK, Fortune SM, Bryson BD -
Markov Field Network Model of Multi-modal Data Predicts Effects of Immune System Perturbations on Intravenous BCG Vaccination in Macaques
Cell SystWang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA -
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
RMD OpenTurcinov S, Sharma RK, De Vries C, Cîrciumaru A, Gerstner C, Mathsson-Alm L, Raposo B, Dubnovitsky A, Rönnblom L, Kwok WW, Chemin K, Malmström V, Hensvold A -
B cell adapter for PI 3-kinase (BCAP) coordinates antigen internalization and trafficking through the B cell receptor.
Sci AdvLagos J, Holder U, Sagadiev S, Montiel-Armendariz A, Li LZ, Pasare C, Hou B, Hamerman JA, Acharya M -
Synovial regulatory T cells expressing ST2 deteriorate joint inflammation through the suppression of immunoregulatory eosinophils.
J AutoimmunHattori K, Tanaka S, Hashiba D, Tamura J, Etori K, Kageyama T, Ito T, Meguro K, Iwata A, Suto A, Suzuki K, Nakamura J, Ohtori S, Ziegler SF, Nakajima H -
Are Glycans Really Non-templated? Deploying AI Deciphers how the Underlying Protein Helps Shape their Glycans
GlycobiologyKellman BP, Sandoval D, Zaytseva OO, Brock K, Baboo S, Nachmanson D, Irvine EB, Armingol E, Mih N, Zhang Y, Jeffris M, Bartels P, Nguyen T, Tam A, Gasman S, Ilan S, Shamie I, Diedrich JK, Wang X, van Woudenbergh E, Altman M, Aylward A, Bao B, Castro A, Sorrentino J, Chiang A, Campbell M, Bartsch Y, Aguilar-Calvo P, Sigurdson C, Alter G, Lauc G, Yates III JR, Marks D, Lisacek F, Mariethoz J, Shaul S, Alteri M, Bojar D, Lewis NE -
An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy.
Cell RepJamison BL, Lawrance M, Wang CJ, DeBerg HA, Ziegler LJ, Sansom DM, Gavin MA, Walker LSK, Campbell DJ -
Antigen-specific T-cell frequency and phenotype mirrors disease activity in DRB1*04:04+ rheumatoid arthritis patients.
Clin Exp ImmunolRims C, Uchtenhagen H, Brooks K, Ng B, Posso SE, Carlin J, Kwok WW, Buckner JH, James EA