-
The path ahead for understanding Toll-like receptors-driven systemic autoimmunity.
Curr Opin ImmunolHamerman JA, Barton GM -
Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers.
DiabetologiaZhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults.
bioRxivGong Q, Sharma M, Kuan EL, Glass MC, Chander A, Singh M, Graybuck LT, Thomson ZJ, LaFrance CM, Zaim SR, Peng T, Okada LY, Genge PC, Henderson KE, Dornisch EM, Layton ED, Wittig PJ, Heubeck AT, Mukuka NM, Reading J, Roll CR, Hernandez V, Parthasarathy V, Stuckey TJ, Musgrove B, Swanson E, Lord C, Weiss MDA, Phalen CG, Mettey RR, Lee KJ, Johanneson JB, Kawelo EK, Garber J, Krishnan U, Smithmyer M, Wherry EJ, Vella L, Henrickson SE, Kopp MS, Savage AK, Becker LA, Meijer P, Coffey EM, Goronzy JJ, Speake C, Bumol TF, Goldrath AW, Torgerson TR, Li XJ, Skene PJ, Buckner JH, Gustafson CE -
Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation.
ElifePahl MC, Sharma P, Thomas RM, Thompson Z, Mount Z, Pippin JA, Morawski PA, Sun P, Su C, Campbell D, Grant SFA, Wells AD -
Clinical and Molecular Analysis of Longitudinal Rhinitis Phenotypes in an Urban Birth Cohort.
J Allergy Clin ImmunolRamratnam SK, Johnson M, Visness CM, Calatroni A, Altman MC, Janczyk T, McCauley KE, Schachtschneider C, Fujimura KE, Fadrosh DW, Lynch SV, Bacharier LB, O'Connor GT, Sandel MT, Kattan M, Wood RA, Gergen PJ, Jackson DJ, Togias A, Gern JE, Childhood Asthma in Urban Settings (CAUSE) network -
Proteomic Differences in Colonic Epithelial Cells in Ulcerative Colitis Have an Epigenetic Basis.
Gastro Hep AdvJelinsky S, Lee I, Monetti M, Breitkopf S, Martz F, Kongala R, Culver J, Vo V, Xue L, Gieseck R 3rd, Dickinson C, Kasaian M, Lord JD -
Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis.
Nat Rev RheumatolHolers VM, Demoruelle KM, Buckner JH, James EA, Firestein GS, Robinson WH, Steere AC, Zhang F, Norris JM, Kuhn KA, Deane KD -
Identification of biomarkers for COVID-19 associated secondary hemophagocytic lymphohistiocytosis.
bioRxivCanny SP, Stanaway IB, Holton SE, Mitchem M, O'Rourke AR, Pribitzer S, Baxter SK, Wurfel MM, Malhotra U, Buckner JH, Bhatraju PK, Morrell ED, Speake C, Mikacenic C, Hamerman JA -
Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review.
AtherosclerosisKumarapperuma H, Chia ZJ, Malapitan SM, Wight TN, Little PJ, Kamato D -
Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.
DiabetesGreenbaum CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, DiMeglio LA, Herold KC, Krischer JP -
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts.
bioRxivDeBerg HA, Fahning ML, Varkhande SR, Schlenker JD, Schmitt WP, Gupta A, Singh A, Gratz IK, Carlin JS, Campbell DJ, Morawski PA -
Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at-risk for type 1 diabetes.
J Clin InvestLledó-Delgado A, Preston-Hurlburt P, Currie S, Clark P, Linsley PS, Long SA, Liu C, Koroleva G, Martins AJ, Tsang JS, Herold KC -
A splice of life: the discovery, function, and clinical implications of FOXP3 isoforms in autoimmune disease.
Int ImmunolWeinstein KN, Domeier PP, Ziegler SF -
Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining.
J Allergy Clin ImmunolJung KH, Argenio KL, Jackson DJ, Miller RL, Perzanowski MS, Rundle AG, Bacharier LB, Busse WW, Cohen RT, Visness CM, Gill MA, Gruchalla RS, Hershey GK, Kado RK, Sherenian MG, Liu AH, Makhija MM, Pillai DK, Rivera-Spoljaric K, Gergen PJ, Altman MC, Sandel MT, Sorkness CA, Kattan M, Lovinsky-Desir S -
Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19.
PLoS OneHolton SE, Mitchem M, Chalian H, Pipavath S, Morrell ED, Bhatraju PK, Hamerman JA, Speake C, Malhotra U, Wurfel MM, Ziegler SE, Mikacenic C
