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Dec 2013
Exonic transcription factor binding directs codon choice and affects protein evolution.
ScienceStergachis AB, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, Raubitschek A, Ziegler SF, LeProust E, Akey J, Stamatoyannopoulos J -
Dec 2013
Basophil depletion downregulates Schistosoma mansoni egg-induced granuloma formation.
Parasitol Int.Anyan WK, Seki T, Kumagai T, Obata-Ninomiya K, Furushima-Shimogawara R, Kwansa-Bentum B, Akao N, Bosompem KM, Boakye DA, Wilson MD, Karasuyama H, Ohta N -
Dec 2013
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
J AutoimmunDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y -
Dec 2013
Acceleration of the loss of the first-phase insulin response during the progression to type 1 diabetes in diabetes prevention trial-type 1 participants.
DiabetesSosenko JM, Skyler JS, Beam CA, Krischer JP, Greenbaum CJ, Mahon J, Rafkin LE, Matheson D, Herold KC, Palmer JP, Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups. -
Dec 2013
Yellow fever vaccination elicits broad functional CD4+ T cell responses that recognize structural and nonstructural proteins.
J VirolJames EA, LaFond RE, Gates TJ, Mai DT, Malhotra U, Kwok WW -
Dec 2013
Anti-cytokine therapies in T1D: Concepts and strategies.
Clin ImmunolNepom GT, Ehlers M, Mandrup-Poulsen T -
Dec 2013
IL-2 therapy in type 1 diabetes: "Trials" and tribulations.
Clin ImmunolLong SA, Buckner JH, Greenbaum CJ -
Dec 2013
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Diabetes EndocrinolRigby MR, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, T1DAL Study Team. -
Dec 2013
Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA.
Ann Rheum DisGan RW, Deane KD, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Holers VM, Norris JM -
Nov 2013
The skin is an important bulwark of acquired immunity against intestinal helminths.
J Exp MedObata-Ninomiya K, Ishiwata K, Tsutsui H, Nei Y, Yoshikawa S, Kawano Y, Minegishi Y, Ohta N, Watanabe N, Kanuka H, Karasuyama H -
Nov 2013
Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
J Exp MedGiltiay NV, Chappell CP, Sun X, Kolhatkar N, Teal TH, Wiedeman AE, Kim J, Tanaka L, Buechler MB, Hamerman JA, Imanishi-Kari T, Clark EA, Elkon KB -
Nov 2013
Cutting edge: identification of the thymic stromal lymphopoietin-responsive dendritic cell subset critical for initiation of type 2 contact hypersensitivity.
J ImmunolKitajima M, Ziegler SF -
Nov 2013
GATA-1 regulates the generation and function of basophils.
Proc Natl Acad Sci U S ANei Y, Obata-Ninomiya K, Tsutsui H, Ishiwata K, Miyasaka M, Matsumoto K, Nakae S, Kanuka H, Inase N, Karasuyama H -
Nov 2013
Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.
DiabetesHerold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, AbATE Study Team. -
Oct 2013
Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.
J Biol ChemViola M, Bartolini B, Vigetti D, Karousou E, Moretto P, Deleonibus S, Sawamura T, Wight TN, Hascall VC, De Luca G, Passi A