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A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice.
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Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.
Clin Exp AllergyHinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A -
Cutting Edge: Integrin α4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis.
Journal of ImmunologyGlatigny S, Wagner CA, Bettelli E -
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The Journal of Allergy and Clinical ImmunologyRenand A, Robinson D, Kwok WW -
Pharmacologic Therapies in Pulmonology and Allergy
Med Clin North AmAyars AG, Altman MC -
Surgical marking pen dye inhibits saphenous vein cell proliferation and migration in saphenous vein graft tissue.
J Vasc SurgKikuchi S, Kenagy RD, Gao L, Wight TN, Azuma N, Sobel M, Clowes AW -
HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression.
DiabetesPugliese A, Boulware D, Yu L, Babu S, Steck AK, Becker D, Rodriguez H, DiMeglio L, Evans-Molina C, Harrison LC, Schatz D, Palmer JP, Greenbaum CJ, Eisenbarth GS, Sosenko JM, Type 1 Diabetes TrialNet Study Group. -
Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.
European Journal of ImmunologyCabrera SM, Wang X, Chen YG, Jia S, Kaldunski ML, Greenbaum CJ, Type 1 Diabetes TrialNet Canakinumab Study Group., Mandrup-Poulsen T, AIDA Study Group., Hessner MJ -
The Role of Autophagy-Related Proteins in Candida albicans Infections.
PathogensTam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM -
Identification of tissue-specific cell death using methylation patterns of circulating DNA.
PNAS USALehmann-Werman R, Neiman D, Zemmour H, Moss J, Magenheim J, Vaknin-Dembinsky A, Rubertsson S, Nellgård B, Blennow K, Zetterberg H, Spalding K, Haller MJ, Wasserfall CH, Schatz DA, Greenbaum CJ, Dorrell C, Grompe M, Zick A, Hubert A, Maoz M, Fendrich V, Bartsch DK, Golan T, Ben Sasson SA, Zamir G, Razin A, Cedar H, Shapiro AM, Glaser B, Shemer R, Dor Y -
αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.
Nat CommunAcharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A -
Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo.
Matrix BiologyKeire PA, Bressler SL, Mulvihill ER, Starcher BC, Kang I, Wight TN -
Conditioning of naive CD4(+) T cells for enhanced peripheral Foxp3 induction by nonspecific bystander inflammation.
Nature ImmunologyThompson LJ, Lai JF, Valladao AC, Thelen TD, Urry ZL, Ziegler SF -
Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.
DiabetesGe Y, Onengut-Gumuscu S, Quinlan AR, Mackey AJ, Wright JA, Buckner JH, Habib T, Rich SS, Concannon P -
CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.
Journal of ImmunologyRoan F, Stoklasek TA, Whalen E, Molitor JA, Bluestone JA, Buckner JH, Ziegler SF