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The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Frontiers in ImmunologyGorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ -
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
CellRojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL -
Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.
ScienceAkilesh HM, Buechler MB, Duggan JM, Hahn WO, Matta B, Sun X, Gessay G, Whalen E, Mason M, Presnell SR, Elkon KB, Lacy-Hulbert A, Barnes BJ, Pepper M, Hamerman JA -
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury.
ScienceHarrison OJ, Linehan JL, Shih HY, Bouladoux N, Han SJ, Smelkinson M, Sen SK, Byrd AL, Enamorado M, Yao C, Tamoutounour S, Van Laethem F, Hurabielle C, Collins N, Paun A, Salcedo R, O'Shea JJ, Belkaid Y -
Identification of Human Antigen-Specific CD4+ T-Cells with Peptide-MHC Multimer Technologies.
Methods in Molecular BiologyKong YY, Kwok WW -
The Use of pMHCII Tetramer Technology for the Identification and Characterization of CD4+ T Cells.
Methods in Molecular BiologyWambre E -
Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease.
Journal of Alzheimer's DiseaseReed MJ, Damodarasamy M, Pathan JL, Chan CK, Spiekerman C, Wight TN, Banks WA, Day AJ, Vernon RB, Keene CD -
Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.
Cellular ImmunologyBlahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum CJ, Kwok WW, James EA -
Cutting Edge: Dynamic Expression of Id3 Defines the Stepwise Differentiation of Tissue-Resident Regulatory T Cells.
Journal of ImmunologySullivan JM, Höllbacher B, Campbell DJ -
Disease-Modifying Therapies in Type 1 Diabetes: A Look into the Future of Diabetes Practice.
DrugsGreenbaum CJ, VanBuecken DE, Lord S -
DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
Journal of ImmunologyJames EA, Gillette L, Durinovic-Belló I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW -
A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.
Front ImmunolYang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW -
Controlled release of monoclonal antibodies from poly-l-lysine-coated alginate spheres within a scaffolded implant mitigates autoimmune responses to transplanted islets and limits systemic antibody toxicity.
Materials Science & Engineering. C, Materials for Biological ApplicationsVernon RB, Gooden MD, Preisinger A, Gebe JA -
Immune Checkpoint Ligand PD-L1 Is Upregulated in Pulmonary Lymphangioleiomyomatosis.
American Journal of Respiratory Cell and Molecular BiologyMaisel K, Merrilees MJ, Atochina-Vasserman EN, Lian L, Obraztsova K, Rue R, Vasserman AN, Zuo N, Angel LF, Gow AJ, Kang I, Wight TN, Eruslanov E, Swartz MA, Krymskaya VP -
Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma.
The Journal of Allergy and Clinical ImmunologyAltman MC, Whalen E, Togias A, O'Connor GT, Bacharier LB, Bloomberg GR, Kattan M, Wood RA, Presnell S, LeBeau P, Jaffee K, Visness CM, Busse WW, Gern JE, +Presnell SR