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Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes.
Genes and ImmunityLinsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ -
Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.
Arthritis RheumatolRims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA -
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
EBioMedicineJames JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, Deane KD, Demoruelle MK, Feser M, O'Dell JR, Weisman MH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Harley JB, Robinson W, Hafler DA, O'Connor KC, Buckner JH, Guthridge JM, Norris JM, Holers VM -
Epithelial cell-derived cytokines: more than just signaling the alarm.
The Journal of Clinical InvestigationRoan F, Obata-Ninomiya K, Ziegler SF -
Treg gene signatures predict and measure type 1 diabetes trajectory.
JCI InsightPesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK -
Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.
Current Diabetes ReportsJohnson MB, Cerosaletti K, Flanagan SE, Buckner JH -
Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.
PNAS USASchrock DC, Leddon SA, Hughson A, Miller J, Lacy-Hulbert A, Fowell DJ -
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
Journal of ImmunologyGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions".
The Journal of Allergy and Clinical ImmunologyDavidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M -
Cell type-specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes.
JCI InsightDufort MJ, Greenbaum CJ, Speake C, Linsley PS -
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes.
JCI InsightLinsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ -
ACC1 determines memory potential of individual CD4(+) T cells by regulating de novo fatty acid biosynthesis.
Nat MetabEndo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ, Nakayama T -
Genetics Coming of Age in Type 1 Diabetes.
Diabetes CareCerolsaletti K, Hao W, Greenbaum CJ -
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.
Diabetes CareSims EK, Bahnson HT, Nyalwidhe J, Haataja L, Davis AK, Speake C, DiMeglio LA, Blum J, Morris MA, Mirmira RG, Nadler J, Mastracci TL, Marcovina S, Qian WJ, Yi L, Swensen AC, Yip-Schneider M, Schmidt CM, Considine RV, Arvan P, Greenbaum CJ, Evans-Molina C, T1D Exchange Residual C-peptide Study Group. -
Characterization of regulatory T cells in obese omental adipose tissue in humans.
European Journal of ImmunologyWu D, Han JM, Yu X, Lam AJ, Hoeppli RE, Pesenacker AM, Huang Q, Chen V, Speake C, Yorke E, Nguyen N, Sampath S, Harris D, Levings MK
