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Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction.
J ImmunolIsaksen DE, Baumann H, Trobridge PA, Farr AG, Levin SD, Ziegler SF -
Immunogenetic analysis suggests different pathogenesis for obese and lean African-Americans with diabetic ketoacidosis.
Diabetes CareUmpierrez GE, Woo W, Hagopian WA, Isaacs SD, Palmer JP, Gaur LK, Nepom GT, Clark WS, Mixon PS, Kitabchi AE -
Allelic variation in transcription modulates MHC class II expression and function.
Microbes InfectBeaty JS, Sukiennicki TL, Nepom GT -
Peptide binding affinity and pH variation establish functional thresholds for activation of HLA-DQ-restricted T cell recognition.
Hum ImmunolKwok WW, Reijonen H, Falk BA, Koelle DM, Nepom GT -
MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition.
Human ImmunologyReichstetter S, Kwok WW, Kochik S, Koelle DM, Beaty JS, Nepom GT -
Radioimmunoassay for glutamic acid decarboxylase-65.
Diabetes Technology & TherapeuticsHao W, Daniels T, Pipeleers DG, Smismans A, Reijonen H, Nepom GT, Lernmark A -
Cellular and molecular characterization of the scurfy mouse mutant.
Journal of ImmunologyClark LB, Appleby MW, Brunkow ME, Wilkinson JE, Ziegler SF, Ramsdell F -
Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism.
J ImmunolLevin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG -
Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer.
Tissue AntigensReichstetter S, Kwok WW, Nepom GT -
Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.
Journal of ImmunologyEttinger RA, Liu AW, Nepom GT, Kwok WW -
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.
Nature GeneticsPuel A, Ziegler SF, Buckley RH, Leonard WJ -
Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.
J ImmunolDoherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT -
Recognition of herpes simplex virus type 2 tegument proteins by CD4 T cells infiltrating human genital herpes lesions.
Journal of VirologyKoelle DM, Frank JM, Johnson ML, Kwok WW -
Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells.
The Journal of Clinical InvestigationHershberg RM, Cho DH, Youakim A, Bradley MB, Lee JS, Framson PE, Nepom GT -
Molecular basis for HLA-DQ associations with IDDM.
DiabetesNepom GT, Kwok WW
