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Defective regulatory and effector T cell functions in patients with FOXP3 mutations.
J Clin InvestBacchetta R, Passerini L, Gambineri E, Dai M, Allan SE, Perroni L, Dagna-Bricarelli F, Sartirana C, Matthes-Martin S, Lawitschka A, Azzari C, Ziegler SF, Levings MK, Roncarolo MG -
Lineage and signal strength determine the inhibitory effect of transforming growth factor beta1 (TGF-beta1) on human antigen-specific Th1 and Th2 memory cells.
J AutoimmunHolzer U, Rieck M, Buckner JH -
Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.
J Clin Endocrinol MetabRedondo MJ, Babu S, Zeidler A, Orban T, Yu L, Greenbaum CJ, Palmer JP, Cuthbertson DD, Eisenbarth GS, Krischer JP, Schatz DA, Diabetes Prevention Trial Type 1 Study Group. -
Insights into transcriptional regulation by FOXP3.
Front BiosciCarson BD, Lopes JE, Soper DM, Ziegler SF -
Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide.
J Exp MedSteere AC, Klitz W, Drouin EE, Falk BA, Kwok WW, Nepom GT, Baxter-Lowe LA -
Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo.
J ImmunolWeber SE, Harbertson J, Godebu E, Mros GA, Padrick RC, Carson BD, Ziegler SF, Bradley LM -
Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individuals.
J ImmunolMacaubas C, Wahlstrom J, Galvão da Silva AP, Forsthuber TG, Sønderstrup G, Kwok WW, DeKruyff RH, Umetsu DT -
Association of tumor necrosis factor alpha polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort.
Arthritis RheumKhanna D, Wu H, Park G, Gersuk V, Gold RH, Nepom GT, Wong WK, Sharp JT, Reed EF, Paulus HE, Tsao BP, Western Consortium of Practicing Rheumatologists. -
Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways.
Arterioscler Thromb Vasc BiolOtsuka G, Agah R, Frutkin AD, Wight TN, Dichek DA -
Progress, but not yet ready for clinical use: interrupting immune-mediated destruction of pancreatic beta cells in type 1 diabetes.
Curr Diab RepGreenbaum CJ -
In vivo sites and cellular mechanisms of T reg cell-mediated suppression.
J Exp MedRudensky AY, Campbell DJ -
Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells.
J ImmunolKohm AP, McMahon JS, Podojil JR, Begolka WS, DeGutes M, Kasprowicz DJ, Ziegler SF, Miller SD -
Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1.
Diabetes CareSosenko JM, Palmer JP, Greenbaum CJ, Mahon J, Cowie C, Krischer JP, Chase HP, White NH, Buckingham B, Herold KC, Cuthbertson D, Skyler JS -
Evaluation of leptin levels in subjects at risk for type 1 diabetes.
J AutoimmunGilliam LK, Jensen RA, Yang P, Weigle DS, Greenbaum CJ, Pihoker C -
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.
J ImmunolYang J, Danke NA, Berger D, Reichstetter S, Reijonen H, Greenbaum CJ, Pihoker C, James EA, Kwok WW