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Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis.
Arthritis RheumSnir O, Bäcklund J, Boström J, Andersson I, Kihlberg J, Buckner JH, Klareskog L, Holmdahl R, Malmström V -
Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.
J ImmunolHabib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum CJ, Rawlings DJ, Buckner JH -
Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22.
Rev Diabet StudCerosaletti K, Buckner JH -
Low-dose antigen promotes induction of FOXP3 in human CD4+ T cells.
J ImmunolLong SA, Rieck M, Tatum M, Bollyky PL, Wu RP, Muller I, Ho JC, Shilling HG, Buckner JH -
Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients.
Arthritis RheumSnir O, Rieck M, Gebe JA, Yue BB, Rawlings CA, Nepom G, Malmström V, Buckner JH -
CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game.
J ImmunolLong SA, Buckner JH -
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.
J Clin InvestMenard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, Meffre E -
An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.
Genes ImmunLong SA, Cerosaletti K, Wan JY, Ho JC, Tatum M, Wei S, Shilling HG, Buckner JH -
Assessment of suppressive capacity by human regulatory T cells using a reproducible, bi-directional CFSE-based in vitro assay.
Methods Mol BiolSchneider A, Buckner JH -
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases.
Nat Rev ImmunolBuckner JH -
HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets.
Arthritis RheumJames EA, Moustakas AK, Bui J, Papadopoulos GK, Bondinas G, Buckner JH, Kwok WW -
Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones.
BloodIsnardi I, Ng YS, Menard L, Meyers G, Saadoun D, Srdanovic I, Samuels J, Berman J, Buckner JH, Cunningham-Rundles C, Meffre E -
Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects.
DiabetesLong SA, Cerosaletti K, Bollyky PL, Tatum M, Shilling H, Zhang S, Zhang ZY, Pihoker C, Sanda S, Greenbaum CJ, Buckner JH -
A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA.
Arthritis RheumKolfenbach JR, Deane KD, Derber LA, O'Donnell C, Weisman MH, Buckner JH, Gersuk VH, Wei S, Mikuls TR, O'Dell J, Gregersen PK, Keating RM, Norris JM, Holers VM -
Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells.
J Leukoc BiolBollyky PL, Falk BA, Wu RP, Buckner JH, Wight TN, Nepom GT
