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Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells.
J Leukoc BiolBollyky PL, Falk BA, Wu RP, Buckner JH, Wight TN, Nepom GT -
Changes in autoreactive T cell avidity during type 1 diabetes development.
Clin ImmunolStandifer NE, Burwell EA, Gersuk VH, Greenbaum CJ, Nepom GT -
CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta.
J ImmunolBollyky PL, Falk BA, Long SA, Preisinger A, Braun KR, Wu RP, Evanko SP, Buckner JH, Wight TN, Nepom GT -
Remodeling rodent models to mimic human type 1 diabetes.
Eur J Immunolvon Herrath M, Nepom GT -
Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms.
J ImmunolGebe JA, Yue BB, Unrath KA, Falk BA, Nepom GT -
H5N1 strain-specific hemagglutinin CD4+ T cell epitopes restricted by HLA DR4.
VaccineYang J, Gebe JA, Huston L, James EA, Tan V, Yue BB, Nepom GT, Kwok WW -
Narcolepsy is strongly associated with the T-cell receptor alpha locus.
Nat GenetHallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Honda Y, Honda M, Högl B, Longstreth WT Jr, Montplaisir J, Kemlink D, Einen M, Chen J, Musone SL, Akana M, Miyagawa T, Duan J, Desautels A, Erhardt C, Hesla PE, Poli F, Frauscher B, Jeong JH, Lee SP, Ton TG, Kvale M, Kolesar L, Dobrovolná M, Nepom GT, Salomon D, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Young T, Peppard P, Tokunaga K, Kwok PY, Risch N, Mignot E -
Genetics of type 1A diabetes.
N Engl J MedConcannon P, Rich SS, Nepom GT -
A real-time polymerase chain reaction assay for the rapid identification of the autoimmune disease-associated allele HLA-DQB1*0602.
Tissue AntigensGersuk VH, Nepom GT -
Animal models of human type 1 diabetes.
Nat Immunolvon Herrath M, Nepom GT -
Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects.
Eur J ImmunolLong SA, Walker MR, Rieck M, James EA, Kwok WW, Sanda S, Pihoker C, Nepom GT, Buckner JH -
The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.
PLoS OneBollyky PL, Bice JB, Sweet IR, Falk BA, Gebe JA, Clark AE, Gersuk VH, Aderem A, Hawn TR, Nepom GT -
Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity.
DiabetologiaMartin-Pagola A, Sisino G, Allende G, Dominguez-Bendala J, Gianani R, Reijonen H, Nepom GT, Ricordi C, Ruiz P, Sageshima J, Ciancio G, Burke GW, Pugliese A -
Approaching the Heisenberg principle of immunology.
Clin ImmunolNepom GT -
Characterization of effector functions of human peptide-specific CD4+ T-cell clones for an intracellular pathogen.
Hum ImmunolKlucar P, Barnes PF, Kong Y, Samten B, Tvinnereim A, Spallek R, Nepom GT, Singh M, Shams H
