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Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
Journal of ImmunologyGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Frontiers in ImmunologyGorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ -
IL-6: a cytokine at the crossroads of autoimmunity.
Current Opinion in ImmunologyJones BE, Maerz MD, Buckner JH -
Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.
Frontiers in ImmunologyDam EM, Maier AC, Hocking AM, Carlin J, Ng B, Buckner JH -
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.
Nature Reviews. RheumatologyHolers VM, Demoruelle MK, Kuhn KA, Buckner JH, Robinson WH, Okamoto Y, Norris JM, Deane KD -
Circulating integrin alpha4/beta7+ lymphocytes targeted by vedolizumab have a pro-inflammatory phenotype.
Clinical ImmunologyLord JD, Long SA, Shows DM, Thorpe J, Schwedhelm K, Chen J, Kita M, Buckner JH -
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
Journal of AutoimmunityPieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V -
Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
DiabetesGreenbaum CJ, Speake C, Krischer J, Buckner JH, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA -
Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".
Science ImmunologyCarmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ -
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
The Journal of Experimental MedicineArkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW -
Understanding and preventing type 1 diabetes through the unique working model of TrialNet.
DiabetologiaBattaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark A, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M -
Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.
Journal of ImmunologyBuckner JH, Greenbaum CJ -
S1P1 deletion differentially affects TH17 and Regulatory T cells.
Scientific ReportsEken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M -
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Journal of ImmunologyMetzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ -
A novel and rapid method to quantify Treg mediated suppression of CD4 T cells.
Journal of Immunological MethodsLong AE, Tatum M, Mikacenic C, Buckner JH
