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Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation.
Mucosal ImmunologyKabata H, Flamar AL, Mahlakõiv T, Moriyama S, Rodewald HR, Ziegler SF, Artis D -
Critical Role of TSLP Receptor on CD4 T Cells for Exacerbation of Skin Inflammation.
Journal of ImmunologyKitajima M, Kubo M, Ziegler SF, Suzuki H -
An accumulation of two populations of dendritic cells in skin-draining lymph nodes in response to the expression of thymic stromal lymphopoietin in the skin.
Cellular ImmunologyOmori-Miyake M, Watarai H, Sato K, Ziegler SF, Yagi J -
Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children.
DiabetesZhao LP, Papadopoulos GK, Kwok WW, Moustakas AK, Bondinas GP, Larsson HE, Ludvigsson J, Marcus C, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal.
DiabetesJames EA, Mallone R, Kent SC, DiLorenzo TP -
Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.
DiabetesArribas-Layton D, Guyer P, Delong T, Dang M, Chow IT, Speake C, Greenbaum CJ, Kwok WW, Baker RL, Haskins K, James EA -
Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity.
Cell ReportsHan CY, Kang I, Harten IA, Gebe JA, Chan CK, Omer M, Alonge KM, den Hartigh LJ, Gomes Kjerulf D, Goodspeed L, Subramanian S, Wang S, Kim F, Birk DE, Wight TN, Chait A -
High-molecular weight hyaluronan attenuates tubulointerstitial scarring in kidney injury.
JCI InsightWang X, Balaji S, Steen EH, Blum AJ, Li H, Chan CK, Manson SR, Lu TC, Rae MM, Austin PF, Wight TN, Bollyky PL, Cheng J, Keswani SG -
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Nature CommunicationsPattwell SS, Arora S, Cimino PJ, Ozawa T, Szulzewsky F, Hoellerbauer P, Bonifert T, Hoffstrom BG, Boiani NE, Bolouri H, Correnti CE, Oldrini B, Silber JR, Squatrito M, Paddison PJ, Holland EC -
MAUDE: inferring expression changes in sorting-based CRISPR screens
Genome Biolde Boer CG, Ray JP, Hacohen N, Regev A -
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function.
Science Translational MedicineHonaker Y, Hubbard N, Xiang Y, Fisher L, Hagin D, Sommer K, Song Y, Yang SJ, Lopez C, Tappen T, Dam EM, Khan I, Hale M, Buckner JH, Scharenberg AM, Torgerson TR, Rawlings DJ -
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation.
The Journal of Allergy and Clinical ImmunologyLeyva-Castillo JM, Galand C, Mashiko S, Bissonnette R, McGurk A, Ziegler SF, Dong C, McKenzie ANJ, Sarfati M, Geha RS -
Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen.
The Journal of Allergy and Clinical ImmunologyLarson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR -
Apoptotic Cell-Directed Resolution of Lung Inflammation Requires Myeloid αv Integrin-Mediated Induction of Regulatory T Lymphocytes.
The American Journal of PathologyZhang A, Lacy-Hulbert A, Anderton S, Haslett C, Savill J -
Notch signalling drives synovial fibroblast identity and arthritis pathology.
NatureWei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT, Accelerating Medicines Partnership Rheumatoid Arthritis & Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Buckner JH, Siebel C, Buckley C, Raychaudhuri, Brenner M
