-
Increased frequencies of myelin oligodendrocyte glycoprotein/MHC class II-binding CD4 cells in patients with multiple sclerosis.
J ImmunolRaddassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA -
Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction.
PLoS OneKhadra A, Pietropaolo M, Nepom GT, Sherman A -
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.
Proc Natl Acad Sci U S ABollyky PL, Wu RP, Falk BA, Lord JD, Long SA, Preisinger A, Teng B, Holt GE, Standifer NE, Braun KR, Xie CF, Samuels PL, Vernon RB, Gebe JA, Wight TN, Nepom GT -
Challenges in the pursuit of immune tolerance.
Immunol RevNepom GT, St Clair EW, Turka LA -
Recurrence of autoimmunity in pancreas transplant patients: research update.
Diabetes Manag (Lond)Pugliese A, Reijonen H, Nepom GT, Burke GW 3rd -
Common variants in P2RY11 are associated with narcolepsy.
Nat GenetKornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, Winkelmann J, Plazzi G, Nevsimalova S, Hong SC, Honda Y, Honda M, Högl B, Ton TG, Montplaisir J, Bourgin P, Kemlink D, Huang YS, Warby S, Einen M, Eshragh JL, Miyagawa T, Desautels A, Ruppert E, Hesla PE, Poli F, Pizza F, Frauscher B, Jeong JH, Lee SP, Strohl KP, Longstreth WT Jr, Kvale M, Dobrovolná M, Ohayon MM, Nepom GT, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Peppard P, Young T, Jennum P, Steinman L, Tokunaga K, Kwok PY, Risch N, Hallmayer J, Mignot E -
A model for harmonizing flow cytometry in clinical trials.
Nat ImmunolMaecker HT, McCoy JP Jr, FOCIS Human Immunophenotyping Consortium., Amos M, Elliott J, Gaigalas A, Wang L, Aranda R, Banchereau J, Boshoff C, Braun J, Korin Y, Reed E, Cho J, Hafler D, Davis M, Fathman CG, Robinson W, Denny T, Weinhold K, Desai B, Diamond B, Gregersen P, Di Meglio P, Nestle FO, Peakman M, Villanova F, Ferbas J, Field E, Kantor A, Kawabata T, Komocsar W, Lotze M, Nepom J, Ochs H, O'Lone R, Phippard D, Plevy S, Rich S, Roederer M, Rotrosen D, Yeh JH, Nepom GT -
The Immune Tolerance Network at 10 years: tolerance research at the bedside.
Nat Rev ImmunolBluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St Clair EW, Turka LA -
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.
Arthritis RheumTan W, Wu H, Zhao J, Derber LA, Lee DM, Shadick NA, Conn DL, Smith EA, Gersuk VH, Nepom GT, Moreland LW, Furst DE, Thompson SD, Jonas BL, Holers VM, Glass DN, Chen PP, Bridges SL Jr, Weinblatt ME, Paulus HE, Tsao BP -
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Clin ImmunolSanda S, Bollyky J, Standifer N, Nepom GT, Hamerman JA, Greenbaum CJ -
Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse.
Cell Mol ImmunolBollyky PL, Evanko SP, Wu RP, Potter-Perigo S, Long SA, Kinsella B, Reijonen H, Guebtner K, Teng B, Chan CK, Braun KR, Gebe JA, Nepom GT, Wight TN -
Prediction and pathogenesis in type 1 diabetes.
ImmunityZiegler AG, Nepom GT -
Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.
DiabetesVendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, Reijonen H, Nepom GT, Burke GW 3rd, Pugliese A -
Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.
Genes ImmunDurinovic-Belló I, Wu RP, Gersuk VH, Sanda S, Shilling HG, Nepom GT -
On-chip activation and subsequent detection of individual antigen-specific T cells.
Anal ChemSong Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, Love JC
