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Seasonal airway microbiome and transcriptome interactions promote childhood asthma exacerbations.
J Allergy Clin ImmunolMcCauley KE, Flynn K, Calatroni A, DiMassa V, LaMere B, Fadrosh DW, Lynch KV, Gill MA, Pongracic JA, Khurana Hershey GK, Kercsmar CM, Liu AH, Johnson CC, Kim H, Kattan M, O'Connor GT, Bacharier LB, Teach SJ, Gergen PJ, Wheatley LM, Togias A, LeBeau P, Presnell S, Boushey HA, Busse WW, Gern JE, Jackson DJ, Altman MC, Lynch SV, National Institute of Allergy and Infectious Diseases–sponsored Inner-City Asthma Consortium. -
Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.
Eur Respir JAl-Shaikhly T, Murphy RC, Parker A, Lai Y, Altman MC, Larmore M, Altemeier WA, Frevert CW, Debley JS, Piliponsky AM, Ziegler SF, Peters MC, Hallstrand TS -
Unique basophil microRNA signature in chronic spontaneous urticaria patients who respond to omalizumab
Clin Exp AllergyAl-Shaikhly T, MacDonald JW, Bammler TK, Altman MC, Ayars AG, Petroni DH, Tilles SA, Henderson WR Jr -
Endotype of allergic asthma with airway obstruction in urban children.
J Allergy Clin ImmunolAltman MC, Calatroni A, Ramratnam S, Jackson DJ, Presnell S, Rosasco MG, Gergen PJ, Bacharier LB, O'Connor GT, Sandel MT, Kattan M, Wood RA, Visness CM, Gern JE, Inner City Asthma Consortium. -
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region
Nat CommunAneas I, Decker DC, Howard CL, Sobreira DR, Sakabe NJ, Blaine KM, Stein MM, Hrusch CL, Montefiori LE, Tena J, Magnaye KM, Clay SM, Gern JE, Jackson DJ, Altman MC, Naureckas ET, Hogarth DK, White SR, Gomez-Skarmeta JL, Schoetler N, Ober C, Sperling AI, Nobrega MA -
Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.
Clin Transl Allergyda Silva Antunes R, Sutherland A, Frazier A, Schulten V, Pomés A, Glesner J, Calatroni A, Altman MC, Wood RA, O'Connor GT, Pongracic JA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Gill M, Liu AH, Zoratti E, Kattan M, Busse PJ, Bacharier LB, Teach SJ, Wheatley LM, Togias A, Busse WW, Jackson DJ, Sette A -
Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.
Genome MedSoliai MM, Kato A, Helling BA, Stanhope CT, Norton JE, Naughton KA, Klinger AI, Thompson EE, Clay SM, Kim S, Celedón JC, Gern JE, Jackson DJ, Altman MC, Kern RC, Tan BK, Schleimer RP, Nicolae DL, Pinto JM, Ober C -
Ignition sequence start: epithelial allergen sensing and regulation of the allergic inflammatory response.
Nat ImmunolMurphy RC, Altman MC -
Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study
Sci ImmunolIMPACC Manuscript Writing Team -
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.
Nat CommunAltman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Syed Ahamed Kabeer B, Alfaki M, Presnell SR, Khaenam P, Ayllón-Benítez A, Mougin F, Thébault P, Chiche L, Jourde-Chiche N, Phillips JT, Klintmalm G, O'Garra A, Berry M, Bloom C, Wilkinson RJ, Graham CM, Lipman M, Lertmemongkolchai G, Bedognetti D, Thiebaut R, Kheradmand F, Mejias A, Ramilo O, Palucka K, Pascual V, Banchereau J, Chaussabel D -
Management Strategies to Reduce Exacerbations in non-T2 Asthma
J Allergy Clin Immunol PractMurphy RC, Pavord ID, Alam R, Altman MC -
Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.
J Allergy Clin ImmunolAltman MC, Flynn K, Rosasco MG, Dapas M, Kattan M, Lovinsky-Desir S, O'Connor GT, Gill MA, Gruchalla RS, Liu AH, Pongracic JA, Khurana Hershey GK, Zoratti EM, Teach SJ, Rastrogi D, Wood RA, Bacharier LB, LeBeau P, Gergen PJ, Togias A, Busse WW, Presnell S, Gern JE, Ober C, Jackson DJ, NIAID Inner City Asthma Consortium. -
Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children
J Allergy Clin ImmunolLeBeau P, Lockhart A, Togias A, Sandel MT, Gereige JD, Bacharier LB, Lovinsky-Desir S, Wood RA, James R, Busse WW, Gern JE, Altman MC -
BloodGen3Module: Blood transcriptional module repertoire analysis and visualization using R.
BioinformaticsRinchai D, Roelands J, Toufiq M, Hendrickx W, Altman MC, Bedognetti D, Chaussabel D -
Extracellular vesicle microRNAs as predictors of response to omalizumab in chronic spontaneous urticaria
AllergyAl-Shaikhly T, MacDonald JW, Bammler TK, Altman MC, Ayars AG, Petroni DH, Tilles SA, Henderson WR Jr