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Low HERV-K(C4) copy number is associated with type 1 diabetes.
DiabetesMason MJ, Speake C, Gersuk VH, Nguyen QA, O'Brien KK, Odegard JM, Buckner JH, Greenbaum CJ, Chaussabel D, Nepom GT -
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
J AutoimmunDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y -
Anti-cytokine therapies in T1D: Concepts and strategies.
Clin ImmunolNepom GT, Ehlers M, Mandrup-Poulsen T -
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Diabetes EndocrinolRigby MR, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, T1DAL Study Team. -
Immunological biomarkers: catalysts for translational advances in autoimmune diabetes.
Clin Exp ImmunolAhmed ST, Akirav E, Bradshaw E, Buckner JH, McKinney E, Quintana FJ, Waldron-Lynch F, Nepom GT -
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.
ImmunityObermoser G, Presnell S, Domico K, Xu H, Wang Y, Anguiano E, Thompson-Snipes L, Ranganathan R, Zeitner B, Bjork A, Anderson D, Speake C, Ruchaud E, Skinner J, Alsina L, Sharma M, Dutartre H, Cepika A, Israelsson E, Nguyen P, Nguyen QA, Harrod AC, Zurawski SM, Pascual V, Ueno H, Nepom GT, Quinn C, Blankenship D, Palucka K, Banchereau J, Chaussabel D -
IL-10 induction from implants delivering pancreatic islets and hyaluronan.
J Diabetes ResBollyky PL, Vernon RB, Falk BA, Preisinger A, Gooden MD, Nepom GT, Gebe JA -
A functional framework for interpretation of genetic associations in T1D.
Curr Opin ImmunolNepom GT, Buckner JH -
T cell autoreactivity in the transplant milieu.
Am J TransplantMatthis J, Nepom GT -
MHC class II tetramers.
J ImmunolNepom GT -
Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration.
Matrix BiolEvanko SP, Potter-Perigo S, Bollyky PL, Nepom GT, Wight TN -
Self-reactive human CD4 T cell clones form unusual immunological synapses.
J Exp MedSchubert DA, Gordo S, Sabatino JJ Jr, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW -
Ultra-sensitive detection of rare T cell clones.
J Immunol MethodsRobins H, Desmarais C, Matthis J, Livingston R, Andriesen J, Reijonen H, Carlson C, Nepom GT, Yee C , Cerosaletti K -
Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor.
Cell TransplantVernon RB, Preisinger A, Gooden MD, D'Amico LA, Yue BB, Bollyky PL, Kuhr CS, Hefty TR, Nepom GT, Gebe JA -
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience.
Rev Diabet StudEhlers MR, Nepom GT
