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Low HERV-K(C4) copy number is associated with type 1 diabetes.
DiabetesMason MJ, Speake C, Gersuk VH, Nguyen QA, O'Brien KK, Odegard JM, Buckner JH, Greenbaum CJ, Chaussabel D, Nepom GT -
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
Journal of AutoimmunityDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y -
Anti-cytokine therapies in T1D: Concepts and strategies.
Clinical ImmunologyNepom GT, Ehlers M, Mandrup-Poulsen T -
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
The Lancet. Diabetes & EndocrinologyRigby MR, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, T1DAL Study Team. -
Immunological biomarkers: catalysts for translational advances in autoimmune diabetes.
Clinical and Experimental ImmunologyAhmed ST, Akirav E, Bradshaw E, Buckner JH, McKinney E, Quintana FJ, Waldron-Lynch F, Nepom GT -
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.
ImmunityObermoser G, Presnell S, Domico K, Xu H, Wang Y, Anguiano E, Thompson-Snipes L, Ranganathan R, Zeitner B, Bjork A, Anderson D, Speake C, Ruchaud E, Skinner J, Alsina L, Sharma M, Dutartre H, Cepika A, Israelsson E, Nguyen P, Nguyen QA, Harrod AC, Zurawski SM, Pascual V, Ueno H, Nepom GT, Quinn C, Blankenship D, Palucka K, Banchereau J, Chaussabel D -
IL-10 induction from implants delivering pancreatic islets and hyaluronan.
Journal of Diabetes ResearchBollyky PL, Vernon RB, Falk BA, Preisinger A, Gooden MD, Nepom GT, Gebe JA -
A functional framework for interpretation of genetic associations in T1D.
Current Opinion in ImmunologyNepom GT, Buckner JH -
T cell autoreactivity in the transplant milieu.
American Journal of TransplantationMatthis J, Nepom GT -
MHC class II tetramers.
Journal of ImmunologyNepom GT -
Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration.
Matrix BiologyEvanko SP, Potter-Perigo S, Bollyky PL, Nepom GT, Wight TN -
Self-reactive human CD4 T cell clones form unusual immunological synapses.
The Journal of Experimental MedicineSchubert DA, Gordo S, Sabatino JJ Jr, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW -
Ultra-sensitive detection of rare T cell clones.
Journal of Immunological MethodsRobins H, Desmarais C, Matthis J, Livingston R, Andriesen J, Reijonen H, Carlson C, Nepom GT, Yee C, Cerosaletti K -
Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor.
Cell TransplantationVernon RB, Preisinger A, Gooden MD, D'Amico LA, Yue BB, Bollyky PL, Kuhr CS, Hefty TR, Nepom GT, Gebe JA -
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience.
The Review of Diabetic StudiesEhlers MR, Nepom GT
