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Generative Design of Antibody Fc-variants with Synthetic and Programmable Functional Profiles
bioRxivIrvine EB, Bikias T, Stampkopoulos E, Frei L, Schürmann N, Warrender AK, Schmid H, Coukos D, Yang H, Minot M, Kelton W, Reddy ST -
Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes
J Clin InvestGabriele Sassi, Pierre Lemaitre, Laia Fernández Calvo, Francesca Lodi, Álvaro Cortés Calabuig, Samal Bissenova, Amber Wouters, Laure Degroote, Marijke Viaene, Niels Vandamme, Lauren Higdon, Peter S Linsley, S Alice Long, Chantal Mathieu, Conny Gysemans -
T-cell responses against CD19-targeted CAR T cells varnimcabtagene autoleucel (ARI-0001): implications for immune response and therapy outcomes
J Immunother CancerAriadna Bartoló-Ibars, Andrea Aran, Alexandra M Johansson, Valentín Ortiz-Maldonado, Nela Klein-González, Anna Alonso-Saladrigues, Eddie James, Alvaro Urbano-Ispizua, Susana Rives, Julio Delgado, Europa Azucena González-Navarro, William W Kwok, Manel Juan -
ATG as disease-modifying therapy for new-onset type 1 diabetes
LancetCate Speake -
A multi-omics recovery factor predicts long COVID in the IMPACC study
J Clin InvestGisela Gabernet, Jessica Maciuch, Jeremy P Gygi, John F Moore, Annmarie Hoch, Caitlin Syphurs, Tianyi Chu, Naresh Doni Jayavelu, David B Corry, Farrah Kheradmand, Lindsey R Baden, Rafick-Pierre Sekaly, Grace A McComsey, Elias K Haddad, Charles B Cairns, Nadine Rouphael, Ana Fernandez-Sesma, Viviana Simon, Jordan P Metcalf, Nelson I Agudelo Higuita, Catherine L Hough , William B Messer, Mark M Davis, Kari C Nadeau, Bali Pulendran, Monica Kraft, Chris Bime, Elaine F Reed, Joanna Schaenman, David J Erle, Carolyn S Calfee, Mark A Atkinson, Scott C Brakenridge, Esther Melamed, Albert C Shaw, David A Hafler, Alison D Augustine , Patrice M Becker, Al Ozonoff, Steven E Bosinger, Walter Eckalbar, Holden T Maecker, Seunghee Kim-Schulze, Hanno Steen, Florian Krammer, Kerstin Westendorf, IMPACC Network, Bjoern Peters, Slim Fourati, Matthew C Altman, Ofer Levy, Kinga K Smolen, Ruth R Montgomery, Joann Diray-Arce, Steven H Kleinstein, Leying Guan, Lauren I R Ehrlich -
Mepolizumab alters gene regulatory networks of nasal airway type-2 and epithelial inflammation in urban children with asthma
Nat CommunCourtney L Gaberino, R Max Segnitz, Kimberly A Dill-McFarland, Leonard B Bacharier, Agustin Calatroni, Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Robyn T Cohen, Rajesh Kumar, Abigail Lang, Gurjit K Khurana Hershey, Michael G Sherenian, Edward M Zoratti, Stephen J Teach, Meyer Kattan , Patrice M Becker, Alkis Togias, William W Busse, Daniel J Jackson, Matthew C Altman -
High-throughput Cell-free Profiling of SARS-CoV-2 RBD Variants Enables Rapid and Quantitative In Vitro Affinity Landscape Mapping
bioRxivGrasemann L, Han J, Tischler J, Arefi F, Gonzalez Castillo MA, Irvine EB, Chen N, Reddy ST, Maerkl SJ -
Loss of the actin remodeling protein Flightless-1 impairs CD8 and regulatory T cell function
J ImmunolMichelle M Lissner, Jenna M Sullivan, Minjian Ni, McKenna Sherve, Anne M Hocking, Jessica A Hamerman, Daniel J Campbell -
Profiling associations of interactive ligand-receptors (HLA class I and KIR gene products) with the progression to type 1 diabetes among seroconverted participants
DiabetologiaLue Ping Zhao, George K Papadopoulos , Benjamin J McFarland, Jay S Skyler, Hemang M Parikh, William W Kwok, Terry P Lybrand, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Screening Lessons from Prediction and Prevention of Type 1 Diabetes
Inflamm Bowel DisCate Speake, Adam Lacy-Hulbert, James Lord, Carla Greenbaum -
TSLP: contrasting roles in cancer
Front ImmunolRemo Poto, Gianni Marone, Steven F Ziegler , Gilda Varricchi -
Prevalence and severity of chronic kidney disease in a population with type 1 diabetes from a United States health system: a real-world cohort study
Lancet Reg Health AmKatherine R Tuttle, Christina L Reynolds, Lindsey M Kornowske, Cami R Jones, Radica Z Alicic, Kenn B Daratha, Joshua J Neumiller, Carla Greenbaum, Meda E Pavkov, Fang Xu, O Kenrik Duru, Susanne B Nicholas, Keith C Norris, CURE-CKD Consortium -
MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury
JCI InsightHarry Pickering, Narges Alipanah-Lechner, Ernie Chen, Dylan Duchen, Holden T Maecker, Seunghee Kim-Schulze, Ruth R Montgomery, Chris Cotsapas, Hanno Steen, Florian Krammer, Charles R Langelier, Ofer Levy, Lindsey R Baden, Esther Melamed, Lauren Ir Ehrlich, Grace A McComsey, Rafick P Sekaly, Charles B Cairns, Elias K Haddad, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough , William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, David J Erle, Joanna Schaenmann, Al Ozonoff, Bjoern Peters, Steven H Kleinstein, Alison D Augustine , Joann Diray-Arce, Patrice M Becker, Nadine Rouphael, Matthew C Altman, Steve Bosinger, Walter Eckalbar, IMPACC Network, Carolyn S Calfee, Oscar A Aguilar, Elaine F Reed, John R Greenland, Daniel R Calabrese -
Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children
Am J Hum GenetEmma E Thompson, Xiaoyuan Zhong, Peter Carbonetto, Andréanne Morin, Jason Willwerscheid, Cynthia M Visness, Leonard B Bacharier, Meyer Kattan , George T O'Connor, Katherine Rivera-Spoljaric, Robert A Wood, Diane R Gold, Gurjit K Khurana Hershey, Christine C Johnson, Rachel L Miller, Christine M Seroogy, Edward M Zoratti, Peter J Gergen, Albert M Levin, Matthew C Altman, Tina Hartert, Matthew Stephens, Daniel J Jackson, James E Gern, Christopher G McKennan, Carole Ober -
Inflammatory Pathways in Residual Asthma Exacerbations Among Mepolizumab-Treated Urban Children: A Secondary Analysis of a Randomized Clinical Trial
JAMA PediatrMatthew C Altman, Tomasz Janczyk, Ryan C Murphy, Naresh Doni Jayavelu, Agustin Calatroni, Meyer Kattan , Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Gurjit K Khurana Hershey, Michael Sherenian, Rajesh Kumar, Rachel G Robison, Rebecca S Gruchalla, George T O'Connor, Edward M Zoratti, Stephen J Teach, Susan V Lynch, Kimberly A Dill-McFarland, Patrice M Becker, Alkis Togias, James E Gern, Leonard B Bacharier, William W Busse, Daniel J Jackson, Inner City Asthma Consortium and Childhood Asthma in Urban Settings Network