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Inflammatory Pathways in Residual Asthma Exacerbations Among Mepolizumab-Treated Urban Children: A Secondary Analysis of a Randomized Clinical Trial
JAMA PediatrMatthew C Altman, Tomasz Janczyk, Ryan C Murphy, Naresh Doni Jayavelu, Agustin Calatroni, Meyer Kattan , Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Gurjit K Khurana Hershey, Michael Sherenian, Rajesh Kumar, Rachel G Robison, Rebecca S Gruchalla, George T O'Connor, Edward M Zoratti, Stephen J Teach, Susan V Lynch, Kimberly A Dill-McFarland, Patrice M Becker, Alkis Togias, James E Gern, Leonard B Bacharier, William W Busse, Daniel J Jackson, Inner City Asthma Consortium and Childhood Asthma in Urban Settings Network -
cytoKernel: robust kernel embeddings for assessing differential expression of single-cell data
BioinformaticsTusharkanti Ghosh, Ryan M Baxter, Souvik Seal, Victor G Lui, Pratyaydipta Rudra, Thao Vu, Elena W Y Hsieh, Debashis Ghosh -
Single-cell transcriptomic profiling of eosinophils and airway immune cells in childhood asthma
J Allergy Clin ImmunolNaresh Doni Jayavelu, Andrew H Liu , Courtney Gaberino, Kristy Freeman, Matthew Lawrance, Stephan Pribitzer, Clara Seifert, Cullen Dutmer, Alkis Togias, Patrice M Becker, William W Busse, Christine A Sorkness, Carmen Mikacenic, Kimberly A Dill-McFarland, Daniel J Jackson, Matthew C Altman -
Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study
Front Med (Lausanne)Jintong Hou, Benjamin Haslund-Gourley, Joann Diray-Arce, Annmarie Hoch, Nadine Rouphael, Patrice M Becker, Alison D Augustine , Al Ozonoff, Leying Guan, Steven H Kleinstein, Bjoern Peters, Elaine Reed, Matt Altman, Charles R Langelier, Holden Maecker, Seunghee Kim, Ruth R Montgomery, Florian Krammer, Michael Wilson, Walter Eckalbar, Steven E Bosinger, Ofer Levy, Hanno Steen, Lindsey B Rosen, Lindsey R Baden, Esther Melamed, Lauren I R Ehrlich, Grace A McComsey, Rafick P Sekaly, Joanna Schaenman, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough , William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, Carolyn S Calfee, David J Erle, IMPACC Network, Lucy F Robinson, Charles B Cairns, Elias K Haddad, Mary Ann Comunale -
Contrasting Adult and Pediatric Populations in a Cohort of At-Risk Relatives in The T1D TrialNet Pathway to Prevention Study
Diabetes CareErin L Templeman, Lauric A Ferrat, Nicholas Thomas, Cate Speake, Diane K Wherrett, Jennifer Sherr, John M Wentworth, Maria J Redondo, Hemang M Parik , Jamie L Felton, Carmella Evans-Molina, Jay Sosenko, Lu You, Richard A Oram, Emily K Sims -
Cockroach immunotherapy modulates dominant T cell responses independent of allergen extract content
J Allergy Clin ImmunolRicardo da Silva Antunes, Aaron Sutherland, Adam Abawi , April Frazier, Anna Pomés, Jill Glesner, Jay E Slater, Samuel T Mindaye, Kate Cho, Grace Zhou, Marie V Ozanne, Agustin Calatroni, Cynthia M Visness, Matthew C Altman, Robert A Wood, George T O'Connor, Jacqueline A Pongracic, Gurjit K Khurana Hershey, Carolyn M Kercsmar, Rebecca S Gruchalla, Michelle Gill, Daniel Searing, Andrew H Liu , Edward Zoratti, Meyer Kattan , Will Sheehan, Leonard B Bacharier, Stephen J Teach, Lisa M Wheatley , Alkis Togias, William W Busse, Daniel J Jackson, Alessandro Sette -
Blood samples collected under anesthesia can be used as a source of non-diseased controls for immune-based assays
Front ImmunolClara Domingo-Vila, Evangelia D Williams, Megan E Smithmyer, Basilin Benson, Lauric A Ferrat, Sefina Arif, Michelle Hudson , Becky Dobbs, Matthew B Johnson , Iain Yardley, Cate Speake, Richard A Oram, Timothy I M Tree, Benjamin J Blaise, EXE-T1D consortium -
Expanding the Case for Hybrid Insulin Peptides in Type 1 Diabetes.
DiabetesCerosaletti K, Kent SC -
Airway Immune Signatures in Severe and Fatal Infection with COVID-19.
Am J Respir Cell Mol BiolDoni Jayavelu N, Qi JJ, Fourati S, Kheradmand F, Langelier CR, Ehrlich LIR, Diray-Arce J, Hoch A, Kraft M, Becker PM, Altman MC, Montgomery RR -
T cell and autoantibody recognition of nucleus-associated islet autoantigens in individuals with type 1 diabetes.
DiabetologiaGuyer P, Seminova K, Lugar M, Manganaro A, Velarde de la Cruz EE, Hartley R, Smithmyer ME, Speake C, Bonifacio E, Kent SC, James EA -
A haplotype-resolved view of human gene regulation.
bioRxivVollger MR, Swanson EG, Neph SJ, Ranchalis J, Munson KM, Ho CH, Cheng YHH, Sedeno-Cortes AE, Fondrie WE, Bohaczuk SC, Dippel MA, Mao Y, Parmalee NL, Mallory BJ, Harvey WT, Kwon Y, Garcia GH, Hoekzema K, Meyer JG, Cicek M, Eichler EE, Noble WS, Witten DM, Bennett JT, Ray JP, Stergachis AB -
Identification of immunogenic commensal antigens using phage display.
Nat ProtocVerma S, Kimmel S, Harrison OJ -
Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications.
Front ImmunolCheng Z, Wang LJ, Honaker Y, Cincotta SA, Page CE, Vollhardt S, Yuan V, Long SA, Xiao Y, Beilke JN, Arron JR, Bluestone JA -
Immunization with full-length TprC variants induces a broad response to surface-exposed epitopes of the Treponema pallidum repeat protein family and is partially protective in the rabbit model of syphilis.
VaccineGiacani L, Romeis E, Haynes A, Molini BJ, Tantalo LC, Xu LH, Trejos AT, Keane J, Mohamed Z, Armstrong TD, Wieland BA, Phung Q, Vyshenska D, Campbell VL, Godornes C, Koelle DM, Reid TB, Wang Y, Vorobieva AA, Wald A, Lieberman NAP, Greninger AL -
A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency.
Cell RepCabrera-Martinez B, Garcia-Perez JE, Baxter RM, Lui VG, Ghosh T, Eken A, Kostka-Newman Z, Garcia JRM, Rahkola J, Gessner RL, Dutmer CM, Klarquist J, Pietras EM, Ghosh D, Johnson SA, Kedl RM, Hsieh EWY
