-
Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial.
Diabetes CareRussell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, Type 1 Diabetes TrialNet Study Group -
Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma.
RespirologyAl-Shaikhly T, Murphy RC, Lai Y, Frevert CW, Debley JS, Ziegler SF, Wong K, Jia G, Holweg CTJ, Peters MC, Hallstrand TS -
Airway Transcriptome Networks Identify Susceptibility to Frequent Asthma Exacerbations in Children.
J Allergy Clin ImmunolPhelan KJ, Dill-McFarland KA, Kothari A, Segnitz RM, Burkle J, Grashel B, Jenkins S, Spagna D, Martin LJ, Haslam DB, Biagini JM, Kalra M, McCoy KS, Ross KR, Jackson DJ, Mersha T, Altman MC, Hershey GKK -
SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity.
Nat CommunJaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C, Iwasaki A, Ring AM -
Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis.
J Exp MedSo L, Obata-Ninomiya K, Hu A, Muir VS, Takamori A, Song J, Buckner JH, Savan R, Ziegler SF -
What Have Mechanistic Studies Taught Us About Childhood Asthma?
J Allergy Clin Immunol PractLaubhahn K, Phelan KJ, Jackson DJ, Altman MC, Schaub B -
CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study.
Diabetes CareWilson DM, Pietropaolo SL, Acevedo-Calado M, Huang S, Anyaiwe D, Scheinker D, Steck AK, Vasudevan MM, McKay SV, Sherr JL, Herold KC, Dunne JL, Greenbaum CJ, Lord SM, Haller MJ, Schatz DA, Atkinson MA, Nelson PW, Pietropaolo M, Type 1 Diabetes TrialNet Study Group -
FOXP3(+) regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.
bioRxivMartinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF -
Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
Cell Rep MedYounginger BS, Mayba O, Reeder J, Nagarkar DR, Modrusan Z, Albert ML, Byrd AL -
Smooth muscle α(v) integrins regulate vascular fibrosis via CD109 downregulation of TGF-β signalling.
Eur Heart J OpenLi Z, Belozertseva E, Parlakian A, Bascetin R, Louis H, Kawamura Y, Blanc J, Gao-Li J, Pinet F, Lacy-Hulbert A, Challande P, Humphrey JD, Regnault V, Lacolley P -
A Functional Genomics Pipeline to Identify High-Value Asthma and Allergy CpGs in the Human Methylome.
J Allergy Clin ImmunolMorin A, Thompson EE, Helling BA, Shorey-Kendrick LE, Faber P, Gebretsadik T, Bacharier LB, Kattan M, O'Connor GT, Rivera-Spoljaric K, Wood RA, Barnes KC, Mathias RA, Altman MC, Hansen K, McEvoy CT, Spindel ER, Hartert T, Jackson DJ, Gern JE, McKennan CG, Ober C, program collaborators for Environmental Influences on Child Health Outcomes and Children’s Respiratory and Environmental Workgroup -
Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial.
J Allergy Clin ImmunolHuffaker MF, Kanchan K, Bahnson HT, Baloh C, Lack G, Nepom GT, Mathias RA -
Epithelial cell-derived cytokine TSLP activates regulatory T cells by enhancing fatty acid uptake.
Sci RepKasuya T, Tanaka S, Tamura J, Etori K, Shoda J, Hattori K, Endo Y, Kitajima M, Kageyama T, Iwamoto T, Yokota M, Iwata A, Suto A, Suzuki K, Suzuki H, Ziegler SF, Nakajima H -
Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.
J Allergy Clin ImmunolMurphy RC, Lai Y, Altman MC, Barrow KA, Dill-McFarland KA, Liu M, Hamerman JA, Lacy-Hulbert A, Piliponsky AM, Ziegler SF, Altemeier WA, Debley JS, Gharib SA, Hallstrand TS -
Cytotoxic CD8(+) T cells target citrullinated antigens in rheumatoid arthritis.
Nat CommunMoon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, Buckner JH, Deane KD, Holers VM, Goodman SM, Donlin LT, Davis MM, Robinson WH
