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T-cell clones identify three distinct epitopes associated with HLA-Dw14.
Hum ImmunolMickelson EM, Masewicz S, Smith A, Petersdorf E, Nepom GT, Martin PJ, Hansen JA -
Structural and functional constraints on HLA class II dimers implicated in susceptibility to insulin dependent diabetes mellitus.
Baillieres Clin Endocrinol MetabKwok WW, Nepom GT -
Alloreactive T-cell clones identify multiple HLA-DQw3 variants.
Hum ImmunolMickelson EM, Masewicz SA, Nepom GT, Martin PJ, Hansen JA -
Association of HLA-Dw16 with rheumatoid arthritis in Yakima Indians. Further evidence for the "shared epitope" hypothesis.
Arthritis RheumWillkens RF, Nepom GT, Marks CR, Nettles JW, Nepom BS -
Investigating the HLA component in rheumatoid arthritis: an additive (dominant) mode of inheritance is rejected, a recessive mode is preferred.
Genet EpidemiolRigby AS, Silman AJ, Voelm L, Gregory JC, Ollier WE, Khan MA, Nepom GT, Thomson G -
Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes.
J Exp MedAndersen LC, Beaty JS, Nettles JW, Seyfried CE, Nepom GT, Nepom BS -
MHC class-II molecules and autoimmunity.
Annu Rev ImmunolNepom GT, Erlich H -
Structural requirements for recognition of the HLA-Dw14 class II epitope: a key HLA determinant associated with rheumatoid arthritis.
Proc Natl Acad Sci U S AHiraiwa A, Yamanaka K, Kwok WW, Mickelson EM, Masewicz S, Hansen JA, Radka SF, Nepom GT -
A unified hypothesis for the complex genetics of HLA associations with IDDM.
DiabetesNepom GT -
HLA and type I diabetes.
Immunol TodayNepom GT -
Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study.
DiabetesMcCulloch DK, Klaff LJ, Kahn SE, Schoenfeld SL, Greenbaum CJ, Mauseth RS, Benson EA, Nepom GT, Shewey L, Palmer JP -
Molecular biology of immune diseases and the immune response.
Immunol TodayNepom GT -
Further DNA sequence microheterogeneity of the HLA-DR4/Dw13 haplotype group: importance of amino acid position 86 of the DR beta 1 chain for T-cell recognition.
Hum ImmunolLang B, Navarrete C, LoGalbo PR, Nepom GT, Silver J, Winchester RJ, Gregersen PK -
HLA heterozygosity in insulin-dependent diabetes is most frequent at the DQ locus.
Scand J ImmunolMichelsen B, Wassmuth R, Ludvigsson J, Lernmark A, Nepom GT, Fisher L -
HLA-DQ beta sequence polymorphism and genetic susceptibility to IDDM.
DiabetesErlich HA, Bugawan TL, Scharf S, Nepom GT, Tait B, Griffith RL
