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Jan 2001
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.
J Clin InvestAlleva DG, Crowe PD, Jin L, Kwok WW, Ling N, Gottschalk M, Conlon PJ, Gottlieb PA, Putnam AL, Gaur A -
Dec 2000
Distinct T cell interactions with HLA class II tetramers characterize a spectrum of TCR affinities in the human antigen-specific T cell response.
J ImmunolReichstetter S, Ettinger RA, Liu AW, Gebe JA, Nepom GT, Kwok WW -
Dec 2000
Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans.
J VirolKoelle DM, Reymond SN, Chen H, Kwok WW, McClurkan C, Gyaltsong T, Petersdorf EW, Rotkis W, Talley AR, Harrison DA -
Sep 2000
Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Liu AW, Nepom GT, Kwok WW -
Aug 2000
Increased frequency of HLA class II alleles DRB1*0301 and DQB1*0201 in Lambert-Eaton myasthenic syndrome without associated cancer.
Hum ImmunolParsons KT, Kwok WW, Gaur LK, Nepom GT -
Apr 2000
HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells.
J ImmunolKwok WW, Liu AW, Novak EJ, Gebe JA, Ettinger RA, Nepom GT, Reymond SN, Koelle DM -
Mar 2000
Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor.
J VirolHaan KM, Kwok WW, Longnecker R, Speck P -
Dec 1999
MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen.
J Clin InvestNovak EJ, Liu AW, Nepom GT, Kwok WW -
Jul 1999
Peptide binding affinity and pH variation establish functional thresholds for activation of HLA-DQ-restricted T cell recognition.
Hum ImmunolKwok WW, Reijonen H, Falk BA, Koelle DM, Nepom GT -
Jul 1999
MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition.
Hum ImmunolReichstetter S, Kwok WW, Kochik S, Koelle DM, Beaty JS, Nepom GT -
Jan 1999
Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer.
Tissue AntigensReichstetter S, Kwok WW, Nepom GT -
Dec 1998
Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Liu AW, Nepom GT, Kwok WW -
Oct 1998
Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.
J ImmunolDoherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT -
Sep 1998
Recognition of herpes simplex virus type 2 tegument proteins by CD4 T cells infiltrating human genital herpes lesions.
J VirolKoelle DM, Frank JM, Johnson ML, Kwok WW -
Aug 1998
Molecular basis for HLA-DQ associations with IDDM.
DiabetesNepom GT, Kwok WW
