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Radioimmunoassay for glutamic acid decarboxylase-65.
Diabetes Technol TherHao W, Daniels T, Pipeleers DG, Smismans A, Reijonen H, Nepom GT, Lernmark A -
Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer.
Tissue AntigensReichstetter S, Kwok WW, Nepom GT -
Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Liu AW, Nepom GT, Kwok WW -
Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.
J ImmunolDoherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT -
Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells.
J Clin InvestHershberg RM, Cho DH, Youakim A, Bradley MB, Lee JS, Framson PE, Nepom GT -
Molecular basis for HLA-DQ associations with IDDM.
DiabetesNepom GT, Kwok WW -
Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes.
J ImmunolBourdette DN, Chou YK, Whitham RH, Buckner JH, Kwon HJ, Nepom GT, Buenafe A, Cooper SA, Allegretta M, Hashim GA, Offner H, Vandenbark AA -
HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments.
Ann Rheum DisO'Dell JR, Nepom BS, Haire C, Gersuk VH, Gaur L, Moore GF, Drymalski W, Palmer W, Eckhoff PJ, Klassen LW, Wees S, Thiele G, Nepom GT -
Promiscuous T-cell recognition of a rubella capsid protein epitope restricted by DRB1*0403 and DRB1*0901 molecules sharing an HLA DR supertype.
Hum ImmunolOu D, Mitchell LA, Décarie D, Tingle AJ, Nepom GT -
Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.
Hum ImmunolDrover S, Kovats S, Masewicz S, Blum JS, Nepom GT -
HLA-DR class II associations with rubella vaccine-induced joint manifestations.
J Infect DisMitchell LA, Tingle AJ, MacWilliam L, Horne C, Keown P, Gaur LK, Nepom GT -
Major histocompatibility complex-directed susceptibility to rheumatoid arthritis.
Adv ImmunolNepom GT -
High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.
J AutoimmunBach JM, Otto H, Nepom GT, Jung G, Cohen H, Timsit J, Boitard C, van Endert PM -
Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire.
J Clin InvestMuraro PA, Vergelli M, Kalbus M, Banks DE, Nagle JW, Tranquill LR, Nepom GT, Biddison WE, McFarland HF, Martin R -
Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis.
Arthritis RheumPenzotti JE, Nepom GT, Lybrand TP
