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In Vivo Expansion of Antigen-Specific Regulatory T Cells through Staggered Fc.IL-2 Mutein Dosing and Antigen-Specific Immunotherapy.
ImmunohorizonsPham MN, Khoryati L, Jamison BL, Hayes E, Sullivan JM, Campbell DJ, Gavin MA -
High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning.
Science AdvancesBecht E, Tolstrup D, Dutertre CA, Morawski PA, Campbell DJ, Ginhoux F, Newell EW, Gottardo R, Headley MB -
ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue.
The Journal of Experimental MedicineMittelsteadt KL, Hayes ET, Campbell DJ -
Designed proteins assemble antibodies into modular nanocages.
ScienceDivine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D -
The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
The Journal of Clinical InvestigationBolouri H, Speake C, Skibinski D, Long SA, Hocking AM, Campbell DJ, Hamerman JA, Malhotra U, Buckner JH, Benaroya Research Institute COVID-19 Research Team. -
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
CellRodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M -
Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
Journal of ImmunologyHayes ET, Hagan CE, Khoryati L, Gavin MA, Campbell DJ -
Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures.
ImmunohorizonsHöllbacher B, Duhen T, Motley S, Klicznik MM, Gratz IK, Campbell DJ -
Circulating TFH cells as a marker for early therapeutic intervention in T1D.
Nature ImmunologyBettelli E, Campbell DJ -
An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice.
Science ImmunologyKhoryati L, Pham MN, Sherve M, Kumari S, Cook K, Pearson J, Bogdani M, Campbell DJ, Gavin MA -
A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin.
Scientific ReportsKlicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK -
Resident memory T cells show that it is never too late to change your ways.
Nature ImmunologyGratz IK, Campbell DJ -
Rapid Light-Dependent Degradation of Fluorescent Dyes in Formulated Serum-Free Media.
ImmunohorizonsMorawski PA, Motley SJ, Campbell DJ -
Peptidase inhibitor 16 identifies a human regulatory T-cell subset with reduced FOXP3 expression over the first year of recent onset type 1 diabetes.
European Journal of ImmunologyHope CM, Welch J, Mohandas A, Pederson S, Hill D, Gundsambuu B, Eastaff-Leung N, Grosse R, Bresatz S, Ang G, Papademetrios M, Zola H, Duhen T, Campbell D, Brown CY, Krumbiegel D, Sadlon T, Couper JJ, Barry SC, Campbell DJ -
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals.
Science ImmunologyKlicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK
