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Type I Interferon-Driven Monocyte Dysregulation and MAS-associated CD8+ T cells During Macrophage Activation Syndrome
bioRxivSusan P Canny, Hannah A DeBerg, Emma L Kuan, Nicholas Moss, Griffin Gessay, Ailing Lu, Amanda Huang, Allison R O’Rourke, Erik D Layton, Paige Bouvatte, Peter J Wittig, Cate Speake, Carmen Mikacenic, Susan Shenoi, Joyce Hui-Yuen, Daniel J Campbell, Betsy J Barnes, Jessica A Hamerman -
Neutrophils have altered response to acute respiratory viral infection in sputum of patients with rheumatoid arthritis
J Allergy Clin Immunol GlobMatthew Lawrance, Naresh Doni Jayavelu, Gabrielle Z Yize Smith-Rockne, Anne Chaize, Vivian Gersuk, Hannah DeBerg, Stephan Pribitzer, Adarsh Manjunath, Matthew C Altman, Cate Speake, Jane H Buckner , Carmen Mikacenic -
Vaccination in individuals with Down syndrome: immune vulnerability, safety, efficacy and opportunities
NPJ VaccinesBernard Khor, Noemi A Spinazzi, Lina R Patel, Erika Chelales, Nicole Baumer, Peter Bulova, Brian Chicoine, Arturo Borzutzky, Hana M El Sahly, Joaquin M Espinosa, Melissa D Gans, Andrew A McCormick, Rebecca Partridge, Eric Rubenstein, Jonathan D Santoro, Cate Speake, Juanita Valdes Camacho, Kishore Vellody -
Hyperglycemia During Acute Pancreatitis and Progression to Early-Onset Diabetes After Recovery: Preliminary Findings From the Diabetes Related to Acute Pancreatitis and Its Mechanisms (DREAM) Study
Diabetes CareKathleen M Dungan, Vernon M Chinchilli, Ariana Pichardo-Lowden, Nazia Raja-Khan, Melena D Bellin, Dhiraj Yadav, Phil A Hart, Marina Basina, James L Buxbaum, Anna Casu, Carmella Evans-Molina, Darwin L Conwell, Evan L Fogel, Chris E Forsmark, Mark O Goodarzi, Rita R Kalyani, Brian T Layden, Sandra M Lord, Georgios I Papachristou, Walter G Park, Richard Pratley, Vikesh K Singh, Cate Speake, Guru Trikudanathan, Maren Laughlin, Frederico G S Toledo, Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC) -
Associations between dietary patterns and diabetes in patients with acute pancreatitis: a cross-sectional analysis from the DREAM study
J NutrDjibril M Ba, Tian Qiu, Nazia Raja-Khan, Sun Qi, Fred Tabung, Kristen M Roberts, Anna E Phillips, Cemal Yazici, Dhiraj Yadav, Elham Afghani, Venkata S Akshintala, Marina Basina, Melena Bellin, James L Buxbaum, Anna Casu, Kathleen Dungan, Carmella Evans-Molina, Evan L Fogel, Chris E Forsmark, Mark O Goodarzi, Brian T Layden, Sandra Lord, Stephen J Pandol, Georgios I Papachristou, Walter G Park, Richard Pratley, Vikesh K Singh, Cate Speake, Frederico G S Toledo, Guru Trikudanathan, Vernon M Chinchilli, Phil A Hart, Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC) -
Multi-omic profiling reveals age-related immune dynamics in healthy adults
NatureQiuyu Gong, Mehul Sharma, Marla C Glass, Emma L Kuan, Aishwarya Chander, Mansi Singh, Lucas T Graybuck, Zachary J Thomson, Christian M LaFrance, Samir Rachid Zaim, Tao Peng, Lauren Y Okada, Palak C Genge, Katherine E Henderson, Elisabeth M Dornisch, Erik D Layton, Peter J Wittig, Alexander T Heubeck, Nelson M Mukuka, Julian Reading, Garrett Strawn, Teminijesu Titus-Adewunmi, Kathleen Abadie, Charles R Roll, Veronica Hernandez, Vaishnavi Parthasarathy, Tyanna J Stuckey, Blessing Musgrove, Elliott Swanson, Cara Lord, Morgan D A Weiss, Cole G Phalen, Regina R Mettey, Kevin J Lee, John B Johanneson, Erin K Kawelo, Jessica Garber, Upaasana Krishnan, Megan Smithmyer, E John Wherry, Laura A Vella, Sarah E Henrickson, Mackenzie S Kopp, Adam K Savage, Lynne A Becker, Paul Meijer, Ernest M Coffey, Jorg J Goronzy, Mikael Sigvardsson, Cate Speake, Thomas F Bumol, Ananda W Goldrath, Troy R Torgerson, Xiao-Jun Li, Peter J Skene, Jane H Buckner , Claire E Gustafson -
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation
Sci Transl MedZiyuan He, Marla C Glass, Pravina Venkatesan, Marie L Feser, Leander Lazaro, Lauren Y Okada, Nhung T T Tran, Yudong D He, Samir Rachid Zaim, Christy E Bennett, Padmapriyadarshini Ravisankar, Elisabeth M Dornisch, Alexandra C Ferrannini, Najeeb A Arishi, Ashley G Asamoah, Saman Barzideh, Lynne A Becker, Elizabeth A Bemis, Jane H Buckner , Christopher E Collora, Megan A L Criley, Kristen Demoruelle M, Chelsie L Fleischer, Jessica Garber, Palak C Genge, Qiuyu Gong, Lucas T Graybuck, Claire E Gustafson, Brian C Hattel, Veronica Hernandez, Alexander T Heubeck, Erin K Kawelo, Upaasana Krishnan, Emma L Kuan, Kristine A Kuhn, Christian M LaFrance, Kevin J Lee, Ruoxin Li, Cara Lord, Regina R Mettey, Laura Moss, Blessing Musgrove, Katherine Hy Nguyen, Andrea Ochoa, Vaishnavi Parthasarathy, Mark-Phillip Pebworth, Chong Pedrick, Tao Peng, Cole G Phalen, Julian Reading, Charles R Roll, Jennifer A Seifert, Marguerite D Siedschlag, Cate Speake, Christopher C Striebich, Tyanna J Stuckey, Elliott G Swanson, Hideto Takada, Tylor Thai, Zachary J Thomson, Nguyen Trieu, Vlad Tsaltskan, Wei Wang, Morgan D A Weiss, Amy Westermann, Fan Zhang, David L Boyle, Ananda W Goldrath, Thomas F Bumol, Xiao-Jun Li, V Michael Holers, Peter J Skene, Adam K Savage, Gary S Firestein, Kevin D Deane, Troy R Torgerson, Mark A Gillespie -
ATG as disease-modifying therapy for new-onset type 1 diabetes
LancetCate Speake -
Screening Lessons from Prediction and Prevention of Type 1 Diabetes
Inflamm Bowel DisCate Speake, Adam Lacy-Hulbert, James Lord, Carla Greenbaum -
Contrasting Adult and Pediatric Populations in a Cohort of At-Risk Relatives in The T1D TrialNet Pathway to Prevention Study
Diabetes CareErin L Templeman, Lauric A Ferrat, Nicholas Thomas, Cate Speake, Diane K Wherrett, Jennifer Sherr, John M Wentworth, Maria J Redondo, Hemang M Parik , Jamie L Felton, Carmella Evans-Molina, Jay Sosenko, Lu You, Richard A Oram, Emily K Sims -
Blood samples collected under anesthesia can be used as a source of non-diseased controls for immune-based assays
Front ImmunolClara Domingo-Vila, Evangelia D Williams, Megan E Smithmyer, Basilin Benson, Lauric A Ferrat, Sefina Arif, Michelle Hudson , Becky Dobbs, Matthew B Johnson , Iain Yardley, Cate Speake, Richard A Oram, Timothy I M Tree, Benjamin J Blaise, EXE-T1D consortium -
T cell and autoantibody recognition of nucleus-associated islet autoantigens in individuals with type 1 diabetes.
DiabetologiaGuyer P, Seminova K, Lugar M, Manganaro A, Velarde de la Cruz EE, Hartley R, Smithmyer ME, Speake C, Bonifacio E, Kent SC, James EA -
Longitudinally stable T cell function and innate immune activation distinguish healthy adult immunotypes.
Sci Transl MedSmithmyer ME, Hu A, Dufort MJ, Hocking AM, Wiedeman AE, Fasano KJ, Torgerson TR, Skene PJ, Reading J, Li X, Gong Q, Long SA, Lacy-Hulbert A, Gustafson CE, Buckner JH, Speake C, members of the BRI Sound Life Project Team, BRI Sound Life Project Team -
Type 1 Diabetes TrialNet: Leading the Charge in Disease Prediction, Prevention, and Immunotherapeutic Mechanistic Understanding
Diabetes CareLaura M Jacobsen, Jamie L Felton, Brandon M Nathan, Cate Speake, Jeffrey Krischer, Kevan C Herold -
A systematic review of machine learning-based prognostic models for acute pancreatitis: Towards improving methods and reporting quality.
PLoS MedCritelli B, Hassan A, Lahooti I, Noh L, Park JS, Tong K, Lahooti A, Matzko N, Adams JN, Liss L, Quion J, Restrepo D, Nikahd M, Culp S, Lacy-Hulbert A, Speake C, Buxbaum J, Bischof J, Yazici C, Evans-Phillips A, Terp S, Weissman A, Conwell D, Hart P, Ramsey M, Krishna S, Han S, Park E, Shah R, Akshintala V, Windsor JA, Mull NK, Papachristou G, Celi LA, Lee P
