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Divergent effects of a Treg-selective IL-2 mutein on influenza-specific T cell responses
J ImmunolJoseph R Albe, Anita Chaudhary, Asheema Khanna, Kristin Weinstein, Steven F Ziegler , Vandana Kalia, Surojit Sarkar, Daniel J Campbell -
Loss of the actin remodeling protein Flightless-1 impairs CD8 and regulatory T cell function
bioRxivMichelle M Lissner, Jenna M Sullivan, Minjian Ni, McKenna Sherve, Anne M Hocking, Jessica A Hamerman, Daniel J Campbell -
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity.
Curr Opin ImmunolWright RC, Campbell DJ, Levings MK -
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts
J Invest DermatolHannah A DeBerg, Mitch L Fahning, Suraj R Varkhande, James D Schlenker, William P Schmitt, Aayush Gupta, Archana Singh, Iris K Gratz, Jeffrey S Carlin, Daniel J Campbell, Peter A Morawski -
An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy.
Cell RepJamison BL, Lawrance M, Wang CJ, DeBerg HA, Ziegler LJ, Sansom DM, Gavin MA, Walker LSK, Campbell DJ -
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts.
bioRxivDeBerg HA, Fahning ML, Varkhande SR, Schlenker JD, Schmitt WP, Gupta A, Singh A, Gratz IK, Carlin JS, Campbell DJ, Morawski PA -
An IL-2 mutein increases IL-10 and CTLA-4-dependent suppression of dendritic cells by regulatory T cells.
bioRxivJamison BL, Lawrance M, Wang CJ, DeBerg HA, Sansom DM, Gavin MA, Walker LSK, Campbell DJ -
MDR1-expressing CD4+ T cells with Th1.17 features resist to neoadjuvant chemotherapy and are associated with breast cancer clinical response
J Immunother CancerDi Roio A, Hubert M, Besson L, Bossennec M, Rodriguez C, Grinberg-Bleyer Y, Lalle G, Moudombi L, Schneider R, Degletagne C, Treilleux I, Campbell DJ, Metzger S, Duhen T, Trédan O, Caux C, Ménétrier-Caux C -
Diminished responses to mRNA-based SARS-CoV-2 vaccines in individuals with rheumatoid arthritis on immune modifying therapies.
JCI InsightKlebanoff SD, Rodda LB, Morishima C, Wener MH, Yuzefpolskiy Y, Bettelli E, Buckner JH, Speake C, Pepper M, Campbell DJ -
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells.
Nat GenetMouri K, Guo MH, de Boer CG, Lissner MM, Harten IA, Newby GA, DeBerg HA, Platt WF, Gentili M, Liu DR, Campbell DJ, Hacohen N, Tewhey R, Ray JP -
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
Nat GenetMouri K, Guo MH, de Boer CG, Lissner MM, Harten IA, Newby GA, DeBerg HA, Platt WF, Gentili M, Liu DR, Campbell DJ, Hacohen N, Tewhey R, Ray JP -
Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity.
CellRodda LB, Morawski PA, Pruner KB, Fahning ML, Howard CA, Franko N, Logue J, Eggenberger J, Stokes C, Golez I, Hale M, Gale M Jr, Chu HY, Campbell DJ, Pepper M -
Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Immune Responses in Multiple Sclerosis Patients.
J ImmunolYuzefpolskiy Y, Morawski P, Fahning M, Speake C, Lord S, Chaudhary A, Morishima C, Wener MH, Kita M, McCarthy L, Buckner JH, Campbell DJ, Bettelli E -
Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells.
ImmunityPeng C, Huggins MA, Wanhainen KM, Knutson TP, Lu H, Georgiev H, Mittelsteadt KL, Jarjour NN, Wang H, Hogquist KA, Campbell DJ, Borges da Silva H, Jameson SC -
In Vivo Expansion of Antigen-Specific Regulatory T Cells through Staggered Fc.IL-2 Mutein Dosing and Antigen-Specific Immunotherapy.
ImmunohorizonsPham MN, Khoryati L, Jamison BL, Hayes E, Sullivan JM, Campbell DJ, Gavin MA
