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TiNKering around with B7H6 ligand may alter lung transplant outcomes
Am J Respir Cell Mol BiolSarah E Holton, Carmen Mikacenic -
Type I Interferon-Driven Monocyte Dysregulation and MAS-associated CD8+ T cells During Macrophage Activation Syndrome
bioRxivSusan P Canny, Hannah A DeBerg, Emma L Kuan, Nicholas Moss, Griffin Gessay, Ailing Lu, Amanda Huang, Allison R O’Rourke, Erik D Layton, Paige Bouvatte, Peter J Wittig, Cate Speake, Carmen Mikacenic, Susan Shenoi, Joyce Hui-Yuen, Daniel J Campbell, Betsy J Barnes, Jessica A Hamerman -
Neutrophils have altered response to acute respiratory viral infection in sputum of patients with rheumatoid arthritis
J Allergy Clin Immunol GlobMatthew Lawrance, Naresh Doni Jayavelu, Gabrielle Z Yize Smith-Rockne, Anne Chaize, Vivian Gersuk, Hannah DeBerg, Stephan Pribitzer, Adarsh Manjunath, Matthew C Altman, Cate Speake, Jane H Buckner , Carmen Mikacenic -
Heterogeneous Causes of Acute Respiratory Distress Syndrome Correlate With Distinct Peripheral Polyunsaturated Fatty Acid Metabolites
FASEB JLaura A Leuenberger, Joseph S Bednash, Evangeline Schott, Carmen Mikacenic, Eric D Morrell, Carson Richardson, Lynn A Fussner, Jeffrey C Horowitz, Rama K Mallampalli, Saame Raza Shaikh, Robert M Tighe, Kymberly M Gowdy -
Immunology of Sepsis
Clin Chest MedEric D Morrell, Carmen Mikacenic -
Single-cell transcriptomic profiling of eosinophils and airway immune cells in childhood asthma
J Allergy Clin ImmunolNaresh Doni Jayavelu, Andrew H Liu , Courtney Gaberino, Kristy Freeman, Matthew Lawrance, Stephan Pribitzer, Clara Seifert, Cullen Dutmer, Alkis Togias, Patrice M Becker, William W Busse, Christine A Sorkness, Carmen Mikacenic, Kimberly A Dill-McFarland, Daniel J Jackson, Matthew C Altman -
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection
Trends in BiotechnologyI Deniz Derman, Mecit Altan Alioglu, Joseph Christakiran Moses, Zissis C Chroneos , Yasar Ozer Yilmaz, Dishary Banerjee, Jonathan Koff, Syed Hasan Askari Rizvi, Danielle Nicole Klunk, Nazmiye Celik, Sirisha Pochareddy, Todd M Umstead, Ilayda Namli , Sarah E Holton, Carmen Mikacenic, Jessica L Thompson, Diana Cadena Castaneda, Danielle Reifsnyder Hickey, Momoka Nagamine, Prajakta Warang, Michael Schotsaert, Phylip Chen, Mark E Peeples, Karolina Palucka, Ibrahim T Ozbolat -
Proteomic Analyses in COVID-19-Associated Secondary Hemophagocytic Lymphohistiocytosis.
Crit Care ExplorCanny SP, Stanaway IB, Holton SE, Mitchem M, O'Rourke AR, Pribitzer S, Baxter SK, Wurfel MM, Malhotra U, Buckner JH, Bhatraju PK, Morrell ED, Speake C, Mikacenic C, Hamerman JA -
Urinary proteomics identifies distinct immunological profiles of sepsis associated AKI sub-phenotypes.
Crit CareStanaway IB, Morrell ED, Mabrey FL, Sathe NA, Bailey Z, Speckmaier S, Lo J, Zelnick LR, Himmelfarb J, Mikacenic C, Evans L, Wurfel MM, Bhatraju PK -
Identification of biomarkers for COVID-19 associated secondary hemophagocytic lymphohistiocytosis.
bioRxivCanny SP, Stanaway IB, Holton SE, Mitchem M, O'Rourke AR, Pribitzer S, Baxter SK, Wurfel MM, Malhotra U, Buckner JH, Bhatraju PK, Morrell ED, Speake C, Mikacenic C, Hamerman JA -
Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19.
PLoS OneHolton SE, Mitchem M, Chalian H, Pipavath S, Morrell ED, Bhatraju PK, Hamerman JA, Speake C, Malhotra U, Wurfel MM, Ziegler SE, Mikacenic C -
PD-L1 and PD-1 Are Associated with Clinical Outcomes and Alveolar Immune Cell Activation in ARDS.
Am J Respir Cell Mol BiolMorrell ED, Holton SE, Wiedeman A, Kosamo S, Mitchem MA, Dmyterko V, Franklin Z, Garay A, Stanaway IB, Liu T, Sathe NA, Mabrey FL, Stapleton RD, Malhotra U, Speake C, Hamerman JA, Pipavath S, Evans L, Bhatraju PK, Long SA, Wurfel MM, Mikacenic C -
The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure.
Nat CommunMorrell ED, Holton SE, Lawrance M, Orlov M, Franklin Z, Mitchem MA, DeBerg H, Gersuk VH, Garay A, Barnes E, Liu T, Peltan ID, Rogers A, Ziegler S, Wurfel MM, Mikacenic C -
Reply: Research Bronchoscopy Standards and the Need for Non-Invasive Sampling of the Failing Lungs.
Ann Am Thorac SocMikacenic C, Fussner LA, Simpson AJ, Singer BD, Files DC -
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia.
EBioMedicineMabrey FL, Nian H, Yu C, Barnes EM, Malhotra U, Mikacenic C, Goldstein J, O'Mahony DS, Garcia-Diaz J, Finn P, Voelker K, Morrell ED, Self WH, Becker PM, Martin TR, Wurfel MM