Morawski Lab

The Morawski Lab studies how adaptive immune responses interact with structural cells during human inflammatory and autoimmune diseases of the skin and other barrier tissues. 

Much of this work examines the reciprocal interactions between immune and structural cells in the skin, including how T cells shape fibroblast cell states and how signals from the tissue, in turn, influence immune function. Lab members integrate human tissue analysis with cellular and molecular approaches, including in situ imaging, organotypic culture, and gene editing, to dissect these interactions. 

A major goal is to understand the immune-stromal networks that maintain tissue homeostasis and how these networks become dysregulated in systemic diseases such as scleroderma and lupus.