The Morawski lab studies the adaptive immune response occurring during human inflammatory and autoimmune diseases of the skin and other barrier tissues.
Our approach integrates cellular and molecular techniques including in situ imaging, organotypic culture, and gene editing to understand how T cells reprogram the structural cells of the skin and in turn how signals from the tissue shape the immune repertoire.
We are especially interested in dissecting the immune-stromal networks that maintain homeostasis in the skin and those that are dysregulated during heterogeneous systemic diseases such as scleroderma and lupus.
Peter Morawski, PhD
Research Projects
Skin T cell control of skin structural cells
Featured Publications
Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity.
Cell
High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning.
Sci Adv
Designed proteins assemble antibodies into modular nanocages.
Science
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
Cell
Rapid Light-Dependent Degradation of Fluorescent Dyes in Formulated Serum-Free Media.
Immunohorizons
Meet BRI's Summer 2023 Interns
Revolutionary Microscope to Fuel Immunology Breakthroughs
Exploring New Frontiers of Skin Immunology
Immune cells perform different functions in different parts of the body. Some fight off infections in the skin. Others protect the lungs from pollutants. But how do these cells learn to do the right job in the right place? And why does that process sometimes go wrong?
