John Ray, PhD

Assistant Member
Office Phone: 

Background Information

John Ray received his BS in Molecular, Cellular and Development Biology at the University of Washington in 2007 and his PhD in Immunobiology at Yale University in 2014, working in the laboratory of Joe Craft, MD. He completed postdoctoral research at the Broad Institute of MIT and Harvard University in the lab of Nir Hacohen, PhD, studying autoimmune-associated genetic variants and epigenetic regulation in immune cell subsets in order to better understand the mechanism for risk at specific loci and global transcriptional deregulation in those susceptible to autoimmunity. Dr. Ray joined the faculty of the Benaroya Research Institution in 2020 and is currently an Assistant Member.

Area of Research

The Ray lab studies the mechanisms that contribute to variation in human immune responses. In particular, we determine how genetic variants and non-coding regulatory regions alter immune responses and confer autoimmune disease susceptibility. With a focus on T cells, we prioritize likely disease-causal genetic variants and enhancers, and, in human and mouse systems, we dissect their mechanisms of action. Understanding the mechanisms of inherited autoimmune disease susceptibility will inform efforts for personalized therapies and disease prevention.

Ray Laboratory

Systems Immunology Division