Jessica A. Hamerman, PhD

Director, Academic Affairs; Member
Office Phone: 

Background Information

Jessica Hamerman received her BS in Biological Sciences from Stanford University and her PhD in Immunology from the University of Washington. She then pursued postdoctoral studies at the University of California San Francisco before joining the Benaroya Research Institute Immunology Program in 2006. Dr. Hamerman is also an Affiliate Associate Professor in the Department of Immunology at the University of Washington School of Medicine.

Area of Research

Projects in Dr. Hamerman’s laboratory are focused on understanding the regulation of the inflammatory response of monocytes, macrophages and dendritic cells, types of immune cells involved in the early defense against infection. Although this inflammatory response is beneficial for pathogen clearance, it can be detrimental if unchecked, leading to autoimmune or inflammatory diseases. Dr. Hamerman’s laboratory examines both how this inflammatory response is regulated in healthy individuals and how it is dysregulated in disease settings, with a focus on rheumatic diseases, including systemic lupus erythematosus and systemic juvenile idiopathic arthritis. Her group uses model systems as well as patient samples available from the BRI Immune Mediated Disease Biorepository to ask these questions. These studies will not only help elucidate how the inflammatory response is regulated during infection, but will potentially give insights in how to manipulate the innate immune system to achieve more efficient elimination of pathogens and to dampen pathogenic inflammatory responses during disease.

Hamerman Laboratory