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Nov 2007
Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.
AtherosclerosisGoueffic Y, Potter-Perigo S, Chan CK, Johnson PY, Braun K, Evanko SP, Wight TN -
Nov 2007
Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice.
AtherosclerosisChira EC, McMillen TS, Wang S, Haw A 3rd, O'Brien KD, Wight TN, Chait A -
Sep 2007
Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion.
DiabetesHan CY, Subramanian S, Chan CK, Omer M, Chiba T, Wight TN, Chait A -
Jul 2007
Cutting edge: high molecular weight hyaluronan promotes the suppressive effects of CD4+CD25+ regulatory T cells.
J ImmunolBollyky PL, Lord JD, Masewicz SA, Evanko SP, Buckner JH, Wight TN, Nepom GT -
Jun 2007
Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells.
J Cell BiochemLemire JM, Chan CK, Bressler S, Miller J, LeBaron RG, Wight TN -
May 2007
Decorin synthesized by arterial smooth muscle cells is retained in fibrin gels and modulates fibrin contraction.
J Cell BiochemJohnson PY, Potter-Perigo S, Gooden MD, Vernon RB, Wight TN -
May 2007
Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration.
Arterioscler Thromb Vasc BiolNakashima Y, Fujii H, Sumiyoshi S, Wight TN, Sueishi K -
Nov 2006
Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice.
J NutrTannock LR, Kirk EA, King VL, LeBoeuf R, Wight TN, Chait A -
Nov 2006
Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.
J Cell SciKuznetsova SA, Issa P, Perruccio EM, Zeng B, Sipes JM, Ward Y, Seyfried NT, Fielder HL, Day AJ, Wight TN, Roberts DD -
Sep 2006
Matricellular hevin regulates decorin production and collagen assembly.
J Biol ChemSullivan MM, Barker TH, Funk SE, Karchin A, Seo NS, Höök M, Sanders J, Starcher B, Wight TN, Puolakkainen P, Sage EH -
Sep 2006
V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis.
Lab InvestMiquel-Serra L, Serra M, Hernández D, Domenzain C, Docampo MJ, Rabanal RM, de Torres I, Wight TN, Fabra A, Bassols A -
Sep 2006
The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells.
Biochim Biophys ActaKaji T, Yamamoto C, Oh-i M, Fujiwara Y, Yamazaki Y, Morita T, Plaas AH, Wight TN -
Aug 2006
Versican degradation and vascular disease.
Trends Cardiovasc MedKenagy RD, Plaas AH, Wight TN -
Jul 2006
A role for decorin in cutaneous wound healing and angiogenesis.
Wound Repair RegenJärveläinen H, Puolakkainen P, Pakkanen S, Brown EL, Höök M, Iozzo RV, Sage EH, Wight TN -
Apr 2006
Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways.
Arterioscler Thromb Vasc BiolOtsuka G, Agah R, Frutkin AD, Wight TN, Dichek DA