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Dec 2012
Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung.
Cell RepJhingran A, Mar KB, Kumasaka DK, Knoblaugh SE, Ngo LY, Segal BH, Iwakura Y, Lowell CA, Hamerman JA, Lin X, Hohl TM -
Jan 2012
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.
Proc Natl Acad Sci U S ANi M, MacFarlane AW 4th, Toft M, Lowell CA, Campbell KS, Hamerman JA -
Jan 2012
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Eur J ImmunolIto H, Hamerman JA -
Mar 2011
S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation.
CirculationAverill MM, Barnhart S, Becker L, Li X, Heinecke JW, Leboeuf RC, Hamerman JA, Sorg C, Kerkhoff C, Bornfeldt KE -
Aug 2010
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Clin ImmunolSanda S, Bollyky J, Standifer N, Nepom GT, Hamerman JA, Greenbaum CJ -
Jun 2010
DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2.
J ImmunolKoth LL, Cambier CJ, Ellwanger A, Solon M, Hou L, Lanier LL, Abram CL, Hamerman JA, Woodruff PG -
Nov 2009
The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.
Immunol RevHamerman JA, Ni M, Killebrew JR, Chu CL, Lowell CA -
Jan 2009
TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
J Cell BiolN'Diaye EN, Branda CS, Branda SS, Nevarez L, Colonna M, Lowell C, Hamerman JA, Seaman WE -
Apr 2008
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Cancer ResEpardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath AW, Turley SJ -
Jan 2008
Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma.
Eur J ImmunolChu CL, Yu YL, Shen KY, Lowell CA, Lanier LL, Hamerman JA