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Jul 2019
Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
DiabetesAhmed S, Cerosaletti K, James EA, Long SA, Mannering SI, Speake C, Nakayama M, Tree T, Roep BO, Herold KC, Brusko TM -
Apr 2019
Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.
Arthritis RheumatolRims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA -
Jan 2019
Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.
Cell ImmunolBlahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum CJ, Kwok WW, James EA -
Dec 2018
DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
J ImmunolJames EA, Gillette L, Durinovic-Belló I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW -
Dec 2018
A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.
Front ImmunolYang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW -
Nov 2018
Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
DiabetesBuitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L -
Oct 2018
Peanut-specific T cell responses in patients with different clinical reactivity.
PLoS OneBirrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V -
Sep 2018
Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B.
CirculationKimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, Strickler HD, Durkin HG, Kassaye SG, Karim R, Tien PC, Landay AL, Gange SJ, Sidney J, Sette A, Ley K -
Sep 2018
Protecting functional β cells with a therapeutic peptide.
Ann Transl MedMarré ML, Piganelli JD, James EA -
Aug 2018
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
J AutoimmunPieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V -
Jul 2018
Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
DiabetesMarré ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA -
Jun 2018
Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance.
DiabetesJames EA, Pietropaolo M, Mamula MJ -
Mar 2018
Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.
DiabetologiaJames EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R, Immunology of Diabetes Society T Cell Workshop Committee. -
Feb 2018
FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity.
Blood AdvEttinger RA, Liberman JA, Gunasekera D, Puranik K, James EA, Thompson AR, Pratt KP -
Jan 2018
T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.
Sci RepReynolds CJ, Suleyman OM, Ortega-Prieto AM, Skelton JK, Bonnesoeur P, Blohm A, Carregaro V, Silva JS, James EA, Maillère B, Dorner M, Boyton RJ, Altmann DM