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Nov 2023
The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure.
Nat CommunMorrell ED, Holton SE, Lawrance M, Orlov M, Franklin Z, Mitchem MA, DeBerg H, Gersuk VH, Garay A, Barnes E, Liu T, Peltan ID, Rogers A, Ziegler S, Wurfel MM, Mikacenic C -
Sep 2023
Reply: Research Bronchoscopy Standards and the Need for Non-Invasive Sampling of the Failing Lungs.
Ann Am Thorac SocMikacenic C, Fussner LA, Simpson AJ, Singer BD, Files DC -
Jun 2023
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia.
EBioMedicineMabrey FL, Nian H, Yu C, Barnes EM, Malhotra U, Mikacenic C, Goldstein J, O'Mahony DS, Garcia-Diaz J, Finn P, Voelker K, Morrell ED, Self WH, Becker PM, Martin TR, Wurfel MM -
May 2023
Research Bronchoscopies in Critically Ill Research Participants: An Official American Thoracic Society Workshop Report.
Ann Am Thorac SocMikacenic C, Fussner LA, Bell J, Burnham EL, Chlan LL, Cook SK, Dickson RP, Almonor F, Luo F, Madan K, Morales-Nebreda L, Mould KJ, Simpson AJ, Singer BD, Stapleton RD, Wendt CH, Files DC -
May 2023
Mediators of monocyte chemotaxis and matrix remodeling are associated with the development of fibrosis in patients with COVID-19.
medRxivHolton SE, Mitchem M, Pipavath S, Morrell ED, Bhatraju PK, Hamerman JA, Speake C, Malhotra U, Wurfel MM, Ziegler S, Mikacenic C -
Apr 2023
Association of Trauma Molecular Endotypes With Differential Response to Transfusion Resuscitation Strategies.
JAMA SurgThau MR, Liu T, Sathe NA, O'Keefe GE, Robinson BRH, Bulger E, Wade CE, Fox EE, Holcomb JB, Liles WC, Stanaway IB, Mikacenic C, Wurfel MM, Bhatraju PK, Morrell ED -
Jan 2023
Alveolar Biomarker Profiles in Subphenotypes of the Acute Respiratory Distress Syndrome.
Crit Care MedSathe NA, Morrell ED, Bhatraju PK, Fessler MB, Stapleton RD, Wurfel MM, Mikacenic C -
Dec 2022
Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity.
Crit Care ExplorBhatraju PK, Morrell ED, Stanaway IB, Sathe NA, Srivastava A, Postelnicu R, Green R, Andrews A, Gonzalez M, Kratochvil CJ, Kumar VK, Hsiang TY, Gale M Jr, Anesi GL, Wyles D, Broadhurst MJ, Brett-Major D, Mukherjee V, Sevransky JE, Landsittel D, Hung C, Altemeier WA, Gharib SA, Uyeki TM, Cobb JP, Liebler JM, Crosslin DR, Jarvik GP, Segal LN, Evans L, Mikacenic C, Wurfel MM -
Dec 2022
Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19.
Crit Care ExplorMabrey FL, Bhatraju PK, Morrell ED, Zelnick LR, Sathe NA, O'Connor NG, Mikacenic C, Martin TR, Liles WC, Wurfel MM -
May 2022
Chemokines, Soluble PD-L1, and Immune Cell Hyporesponsiveness are Distinct Features of SARS-CoV-2 Critical Illness.
Am J Physiol Lung Cell Mol PhysiolMorrell ED, Bhatraju PK, Sathe NA, Lawson J, Mabrey L, Holton SE, Presnell SR, Wiedeman A, Acosta-Vega C, Mitchem MA, Liu T, Chai XY, Sahi S, Brager C, Orlov M, Sakr SS, Sader A, Lum DM, Koetje N, Garay A, Barnes E, Cromer G, Bray MK, Pipavath S, Fink SL, Evans L, Long SA, West TE, Wurfel MM, Mikacenic C -
May 2022
CXCL10 and Soluble Programmed Death-Ligand 1 during Respiratory Viral Infections Are Associated with Chronic Lung Allograft Dysfunction in Lung Transplant Recipients.
Am J Respir Cell Mol BiolMorrell ED, Brager C, Ramos KJ, Chai XY, Kapnadak SG, Edelman J, Matute-Bello G, Altemeier WA, Hwang B, Mulligan MS, Bhatraju PK, Wurfel MM, Mikacenic C, Lease ED, Limaye AP, Fisher CE -
Mar 2022
Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness.
Crit Care MedMikacenic C, Bhatraju P, Robinson-Cohen C, Kosamo S, Fohner AE, Dmyterko V, Long SA, Cerosaletti K, Calfee CS, Matthay MA, Walley KR, Russell JA, Christie JD, Meyer NJ, Christiani DC, Wurfel MM -
Feb 2022
MAP2K2 Delays Recovery in Murine Models of Acute Lung Injury and Associates with ARDS Outcome.
Am J Respir Cell Mol BiolGong KQ, Mikacenic C, Long ME, Frevert C, Birkland TP, Charron J, Gharib SA, Manicone AM -
Feb 2022
Relationships Between Age, Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), and Mortality Among Critically Ill Adults: A Cohort Study.
ShockSathe NA, Bhatraju PK, Mikacenic C, Morrell ED, Mabrey FL, Liles WC, Wurfel MM -
Feb 2022
Differences between Children and Adults with COVID-19: It's Right under Our Nose.
Am J Respir Cell Mol BiolMorrell ED, Mikacenic C