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    • Mar 2025

      Defining a novel DYRK1A-gp130/IL-6R-pSTAT axis that regulates Th17 differentiation.

      Immunohorizons
      Malueg M, Moo KG, Arnett A, Edwards TH, Ruskin SL, Lambert K, Subramanyam A, Dufort MJ, Gersuk VH, Partridge R, Buckner JH, Khor B
    • May 2023

      Down syndrome: insights into autoimmune mechanisms.

      Nat Rev Rheumatol
      Khor B, Buckner JH
    • Dec 2022

      FRTX-02, a selective and potent inhibitor of DYRK1A, modulates inflammatory pathways in mouse models of psoriasis and atopic dermatitis.

      J Transl Autoimmun
      Kim S, Ko E, Choi HG, Kim D, Luchi M, Khor B, Kim S
    • Jan 2022

      Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.

      Sci Transl Med
      Lambert K, Moo KG, Arnett A, Goel G, Hu A, Flynn KJ, Speake C, Wiedeman AE, Gersuk VH, Linsley PS, Greenbaum CJ, Long SA, Partridge R, Buckner JH, Khor B
    • Aug 2021

      The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.

      Mol Cell Biol
      Arnett A, Moo KG, Flynn KJ, Sundberg TB, Johannessen L, Shamji AF, Gray NS, Decker T, Zheng Y, Gersuk VH, Rahman ZS, Levy DE, Marié IJ, Linsley PS, Xavier RJ, Khor B
    • Aug 2021

      Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.

      Elife
      Marié IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy DE
    • Apr 2021

      Two roads diverged: Emerging lessons from IVIG about hemolysis.

      Transfusion
      Asif M, Khor B
    • Jan 2021

      Opportunities, barriers, and recommendations in down syndrome research.

      Transl Sci Rare Dis
      Hendrix JA, Amon A, Abbeduto L, Agiovlasitis S, Alsaied T, Anderson HA, Bain LJ, Baumer N, Bhattacharyya A, Bogunovic D, Botteron KN, Capone G, Chandan P, Chase I, Chicoine B, Cieuta-Walti C, DeRuisseau LR, Durand S, Esbensen A, Fortea J, Giménez S, Granholm AC, Hahn LJ, Head E, Hillerstrom H, Jacola LM, Janicki MP, Jasien JM, Kamer AR, Kent RD, Khor B, Lawrence JB, Lemonnier C, Lewanda AF, Mobley W, Moore PE, Nelson LP, Oreskovic NM, Osorio RS, Patterson D, Rasmussen SA, Reeves RH, Roizen N, Santoro S, Sherman SL, Talib N, Tapia IE, Walsh KM, Warren SF, White AN, Wong GW, Yi JS
Benaroya Research Institute

1201 Ninth Avenue
Seattle, WA 98101-2795
(206) 342-6500

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