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Mar 2024
Investigating Associations between HLA-DR Genotype, H. pylori Infection, and Anti-CagA IgA Seropositivity in a Turkish Gastritis Cohort.
Genes (Basel)Karataş L, Tatar Z, James EA, Colakogullari M -
Feb 2024
CD4+ T cells from individuals with type 1 diabetes respond to a novel class of deamidated peptides formed in pancreatic islets.
DiabetesCallebaut A, Guyer P, Derua R, Buitinga M, Manganaro A, Yi X, Sodré FMC, Vig S, Suleiman M, Marchetti P, Eizirik DL, Kent SC, Mathieu C, James EA, Overbergh L -
Jan 2024
An Insulin-Chromogranin A Hybrid Peptide activates DR11 restricted T cells in human type 1 diabetes.
DiabetesCallebaut A, Guyer P, Baker RL, Gallegos JB, Hohenstein AC, Gottlieb PA, Mathieu C, Overbergh L, Haskins K, James EA -
Nov 2023
Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis.
Nat CommunJames EA, Holers VM, Iyer R, Prideaux EB, Rao NL, Rims C, Muir VS, Posso SE, Bloom MS, Zia A, Elliott SE, Adamska JZ, Ai R, Brewer RC, Seifert JA, Moss L, Barzideh S, Demoruelle MK, Striebich CC, Okamoto Y, Sainbayar E, Crook AA, Peterson RA, Vanderlinden LA, Wang W, Boyle DL, Robinson WH, Buckner JH, Firestein GS, Deane KD -
Sep 2023
The Beta Cell-Immune Cell Interface in Type 1 Diabetes (T1D).
Mol MetabJames EA, Joglekar AV, Linnemann AK, Russ HA, Kent SC -
Aug 2023
Editorial: Processing, presentation, and recognition of T cell determinants: From molecular insights to clinical applications.
Cell ImmunolJames EA -
Jul 2023
Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.
J Clin Endocrinol MetabEttinger RA, Buitinga M, Vandamme C, Afonso G, Gomez R, Arribas-Layton D, Bissenova S, Speake C, Reijonen H, Kinnunen T, Overbergh L, Mallone R, Kwok WW, James EA -
May 2023
Autoimmune susceptible HLA class II motifs facilitate the presentation of modified neoepitopes to potentially autoreactive T cells.
Cell ImmunolMoustakas AK, Nguyen H, James EA, Papadopoulos GK -
Jan 2023
Cytotoxic CD8(+) T cells target citrullinated antigens in rheumatoid arthritis.
Nat CommunMoon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, Buckner JH, Deane KD, Holers VM, Goodman SM, Donlin LT, Davis MM, Robinson WH -
Jan 2023
Characterizing T cell responses to enzymatically modified beta cell neo-epitopes.
Front ImmunolNguyen H, Arribas-Layton D, Chow IT, Speake C, Kwok WW, Hessner MJ, Greenbaum CJ, James EA -
Oct 2022
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Sci Transl MedChriswell ME, Lefferts AR, Clay MR, Hsu AR, Seifert J, Feser ML, Rims C, Bloom MS, Bemis EA, Liu S, Maerz MD, Frank DN, Demoruelle MK, Deane KD, James EA, Buckner JH, Robinson WH, Holers VM, Kuhn KA -
Oct 2022
Autoantibody and T cell responses to oxidative post-translationally modified insulin neoantigenic peptides in type 1 diabetes.
DiabetologiaStrollo R, Vinci C, Man YKS, Bruzzaniti S, Piemonte E, Alhamar G, Briganti SI, Malandrucco I, Tramontana F, Fanali C, Garnett J, Buccafusca R, Guyer P, Mamula M, James EA, Pozzilli P, Ludvigsson J, Winyard PG, Galgani M, Nissim A -
Oct 2022
Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes.
DiabetesGuyer P, Arribas-Layton D, Manganaro A, Speake C, Lord S, Eizirik DL, Kent SC, Mallone R, James EA -
Sep 2022
Editorial: alternative antigen processing and presentation in immune disorders.
Front ImmunolAlvarez I, Antón LC, James EA -
Sep 2022
Mechanism-driven strategies for prevention of rheumatoid arthritis.
Rheumatol AutoimmunHolers VM, Kuhn KA, Demoruelle MK, Norris JM, Firestein GS, James EA, Robinson WH, Buckner JH, Deane KD