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Differential effects of exogenous and endogenous hyaluronan on contraction and strength of collagen gels.
Acta BiomaterAllison DD, Braun KR, Wight TN, Grande-Allen KJ -
The accumulation of versican in the nodules of benign prostatic hyperplasia.
ProstateTrue LD, Hawley S, Norwood TH, Braun KR, Evanko SP, Chan CK, LeBaron RC, Wight TN -
Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content.
J Biol ChemSakr SW, Potter-Perigo S, Kinsella MG, Johnson PY, Braun KR, Goueffic Y, Rosenfeld ME, Wight TN -
Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury.
Am J PatholHwang JY, Johnson PY, Braun KR, Hinek A, Fischer JW, O'Brien KD, Starcher B, Clowes AW, Merrilees MJ, Wight TN -
Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican.
Arterioscler Thromb Vasc BiolSeidelmann SB, Kuo C, Pleskac N, Molina J, Sayers S, Li R, Zhou J, Johnson P, Braun K, Chan C, Teupser D, Breslow JL, Wight TN, Tall AR, Welch CL -
Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.
Circ ResTran-Lundmark K, Tran PK, Paulsson-Berne G, Fridén V, Soininen R, Tryggvason K, Wight TN, Kinsella MG, Borén J, Hedin U -
Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans.
Cardiovasc ResNakashima Y, Wight TN, Sueishi K -
Endogenous overexpression of hyaluronan synthases within dynamically cultured collagen gels: Implications for vascular and valvular disease.
BiomaterialsAllison DD, Wight TN, Ripp NJ, Braun KR, Grande-Allen KJ -
The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells.
Arch Physiol BiochemNigro J, Potter-Perigo S, Ivey ME, de Dios ST, Evanko SP, Wight TN, Little PJ -
Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease.
Respir ResMerrilees MJ, Ching PS, Beaumont B, Hinek A, Wight TN, Black PN -
Lung lining fluid glutathione attenuates IL-13-induced asthma.
Am J Respir Cell Mol BiolLowry MH, McAllister BP, Jean JC, Brown LA, Hughey RP, Cruikshank WW, Amar S, Lucey EC, Braun K, Johnson P, Wight TN, Joyce-Brady M -
Arterial remodeling in vascular disease: a key role for hyaluronan and versican.
Front BiosciWight TN -
Perlecan: a major IL-2-binding proteoglycan in murine spleen.
Immunol Cell BiolMiller JD, Stevens ET, Smith DR, Wight TN, Wrenshall LE -
The effect of endogenous overexpression of hyaluronan synthases on material, morphological, and biochemical properties of uncrosslinked collagen biomaterials.
BiomaterialsAllison DD, Vasco N, Braun KR, Wight TN, Grande-Allen KJ -
Hyaluronan-dependent pericellular matrix.
Adv Drug Deliv RevEvanko SP, Tammi MI, Tammi RH, Wight TN