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Extracellular matrix components in the pathogenesis of type 1 diabetes.
Curr Diab RepBogdani M, Korpos E, Simeonovic CJ, Parish CR, Sorokin L, Wight TN -
Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
J Allergy Clin ImmunolReeves SR, Kolstad T, Lien TY, Elliott M, Ziegler SF, Wight TN, Debley JS -
Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis.
DiabetesBogdani M, Johnson PY, Potter-Perigo S, Nagy N, Day AJ, Bollyky PL, Wight TN -
Versican and the regulation of cell phenotype in disease.
Biochim Biophys ActaWight TN, Kinsella MG, Evanko SP, Potter-Perigo S, Merrilees MJ -
Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.
J Biol ChemKang I, Yoon DW, Braun KR, Wight TN -
Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation.
Immunol ResRuppert SM, Hawn TR, Arrigoni A, Wight TN, Bollyky PL -
Versican and the control of inflammation.
Matrix BiolWight TN, Kang I, Merrilees MJ -
A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.
Matrix BiolChang MY, Tanino Y, Vidova V, Kinsella MG, Chan CK, Johnson PY, Wight TN, Frevert CW -
ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro.
J Histochem CytochemObika M, Vernon RB, Gooden MD, Braun KR, Chan CK, Wight TN -
Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.
J Biol ChemViola M, Bartolini B, Vigetti D, Karousou E, Moretto P, Deleonibus S, Sawamura T, Wight TN, Hascall VC, De Luca G, Passi A -
Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.
Mech DevWilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW -
miRNAs regulate expression and function of extracellular matrix molecules.
Matrix BiolRutnam ZJ, Wight TN, Yang BB -
Sputum hyaluronan and versican in severe eosinophilic asthma.
Int Arch Allergy ImmunolAyars AG, Altman LC, Potter-Perigo S, Radford K, Wight TN, Nair P -
Cleavage of hyaluronan is impaired in aged dermal wounds.
Matrix BiolReed MJ, Damodarasamy M, Chan CK, Johnson MN, Wight TN, Vernon RB -
Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.
J Biol ChemHull RL, Peters MJ, Perigo SP, Chan CK, Wight TN, Kinsella MG