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T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.
BloodEttinger RA, Paz P, James EA, Gunasekera D, Aswad F, Thompson AR, Matthews DC, Pratt KP -
A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.
Arthritis RheumatolScholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Alvarez I -
Immune recognition of citrullinated epitopes.
ImmunologyNguyen H, James EA -
Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.
Nat CommunUchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA -
Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.
Clin Exp AllergyHinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A -
Expanding antigen-specific regulatory networks to treat autoimmunity.
NatureClemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, Tsai S, Wang J, Garabatos N, Izquierdo C, Agrawal S, Keough MB, Yong VW, James EA, Moore A , Yang Y , Stratmann T , Serra P , Santamaria P -
Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.
PLoS PathogJames EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW -
T cell epitopes and post-translationally modified epitopes in type 1 diabetes.
Curr Diab RepMcGinty JW, Marré ML, Bajzik V, Piganelli JD, James EA -
β cell ER stress and the implications for immunogenicity in type 1 diabetes.
Front Cell Dev BiolMarré ML, James EA, Piganelli JD -
Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.
BloodGunasekera D, Ettinger RA, Nakaya Fletcher S, James EA, Liu M, Barrett JC, Withycombe J, Matthews DC, Epstein MS, Hughes RJ, Pratt KP, Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators. -
Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.
J AutoimmunAlvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D -
Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.
PLoS OneChow IT, Yang J, Gates TJ, James EA, Mai DT, Greenbaum CJ, Kwok WW -
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
Proc Natl Acad Sci U S AYang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW -
Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.
DiabetesMcGinty JW, Chow IT, Greenbaum CJ, Odegard JM, Kwok WW, James EA -
Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy.
Clin Exp AllergyArchila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW
