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The biochemistry and immunohistochemistry of versican.
Methods Cell BiolEvanko SP, Chan CK, Johnson PY, Frevert CW, Wight TN -
Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
Am J Physiol Lung Cell Mol PhysiolChang MY, Kang I, Gale M Jr, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW -
Crosstalk Between T Lymphocytes and Lung Fibroblasts: Generation of a Hyaluronan-Enriched Extracellular Matrix Adhesive for Monocytes.
J Cell BiochemGaucherand L, Falk BA, Evanko SP, Workman G, Chan CK, Wight TN -
Provisional matrix: A role for versican and hyaluronan.
Matrix BiolWight TN -
Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging.
J Gerontol A Biol Sci Med SciReed MJ, Vernon RB, Damodarasamy M, Chan CK, Wight TN, Bentov I, Banks WA -
A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis.
Eur Respir JDasgupta A, Kjarsgaard M, Capaldi D, Radford K, Aleman F, Boylan C, Altman LC, Wight TN, Parraga G, O'Byrne PM, Nair P -
Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling.
FASEB JBalaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG -
Interplay of extracellular matrix and leukocytes in lung inflammation.
Cell ImmunolWight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF -
Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation.
J Biol ChemKang I, Harten IA, Chang MY, Braun KR, Sheih A, Nivison MP, Johnson PY, Workman G, Kaber G, Evanko SP, Chan CK, Merrilees MJ, Ziegler SF, Kinsella MG, Frevert CW, Wight TN -
Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin.
J Tissue Eng Regen MedMerrilees MJ, Falk BA, Zuo N, Dickinson ME, May BC, Wight TN -
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.
Sci Transl MedHundhausen C, Roth A, Whalen E, Chen J, Schneider A, Long SA, Wei S, Rawlings R, Kinsman M, Evanko SP, Wight TN, Greenbaum CJ, Cerosaletti K, Buckner JH -
Versican accumulates in vascular lesions in pulmonary arterial hypertension.
Pulm CircChang YT, Chan CK, Eriksson I, Johnson PY, Cao X, Westöö C, Norvik C, Andersson-Sjöland A, Westergren-Thorsson G, Johansson S, Hedin U, Kjellén L, Wight TN, Tran-Lundmark K -
The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.
Clin Exp ImmunolKuipers HF, Nagy N, Ruppert SM, Sunkari VG, Marshall PL, Gebe JA, Ishak HD, Keswani SG, Bollyky J, Frymoyer AR, Wight TN, Steinman L, Bollyky PL -
G1 Domain of Versican Regulates Hyaluronan Organization and the Phenotype of Cultured Human Dermal Fibroblasts.
J Histochem CytochemMerrilees MJ, Zuo N, Evanko SP, Day AJ, Wight TN -
Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma.
J Histochem CytochemReeves SR, Kaber G, Sheih A, Cheng G, Aronica MA, Merrilees MJ, Debley JS, Frevert CW, Ziegler SF, Wight TN
