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The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages.
J ImmunolTampella G, Kerns HM, Niu D, Singh S, Khim S, Bosch KA, Garrett ME, Moguche A, Evans E, Browning B, Jahan TA, Nacht M, Wolf-Yadlin A, Plebani A, Hamerman JA, Rawlings DJ, James RG -
Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
J Exp MedGiltiay NV, Chappell CP, Sun X, Kolhatkar N, Teal TH, Wiedeman AE, Kim J, Tanaka L, Buechler MB, Hamerman JA, Imanishi-Kari T, Clark EA, Elkon KB -
TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury.
PLoS OneCampanholle G, Mittelsteadt K, Nakagawa S, Kobayashi A, Lin SL, Gharib SA, Heinecke JW, Hamerman JA, Altemeier WA, Duffield JS -
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
J ImmunolSun X, Wiedeman A, Agrawal N, Teal TH, Tanaka L, Hudkins KL, Alpers CE, Bolland S, Buechler MB, Hamerman JA, Ledbetter JA, Liggitt D, Elkon KB -
β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.
Eur J ImmunolYee NK, Hamerman JA -
Cutting edge: Type I IFN drives emergency myelopoiesis and peripheral myeloid expansion during chronic TLR7 signaling.
J ImmunolBuechler MB, Teal TH, Elkon KB, Hamerman JA -
Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung.
Cell RepJhingran A, Mar KB, Kumasaka DK, Knoblaugh SE, Ngo LY, Segal BH, Iwakura Y, Lowell CA, Hamerman JA, Lin X, Hohl TM -
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.
Proc Natl Acad Sci U S ANi M, MacFarlane AW 4th, Toft M, Lowell CA, Campbell KS, Hamerman JA -
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Eur J ImmunolIto H, Hamerman JA -
S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation.
CirculationAverill MM, Barnhart S, Becker L, Li X, Heinecke JW, Leboeuf RC, Hamerman JA, Sorg C, Kerkhoff C, Bornfeldt KE -
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Clin ImmunolSanda S, Bollyky J, Standifer N, Nepom GT, Hamerman JA, Greenbaum CJ -
DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2.
J ImmunolKoth LL, Cambier CJ, Ellwanger A, Solon M, Hou L, Lanier LL, Abram CL, Hamerman JA, Woodruff PG -
The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.
Immunol RevHamerman JA, Ni M, Killebrew JR, Chu CL, Lowell CA -
TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
J Cell BiolN'Diaye EN, Branda CS, Branda SS, Nevarez L, Colonna M, Lowell C, Hamerman JA, Seaman WE -
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Cancer ResEpardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath AW, Turley SJ
