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Foxp3 is required throughout the life of a regulatory T cell.
Science's STKELopes JE, Soper DM, Ziegler SF -
IL-2Rbeta links IL-2R signaling with Foxp3 expression.
European Journal of ImmunologySoper DM, Kasprowicz DJ, Ziegler SF -
Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development.
Nature ImmunologyAstrakhan A, Omori M, Nguyen T, Becker-Herman S, Iseki M, Aye T, Hudkins K, Dooley J, Farr A, Alpers CE, Ziegler SF, Rawlings DJ -
Impaired T cell receptor signaling in Foxp3+ CD4 T cells.
Annals of the New York Academy of SciencesCarson BD, Ziegler SF -
FOXP3 modifies the phenotypic and functional properties of regulatory T cells.
Nature Reviews. ImmunologyCampbell DJ, Ziegler SF -
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells.
The Journal of Experimental MedicineAllakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S, Paquette N, Ziegler SF, Sarfati M, Delespesse G -
Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.
The Journal of Clinical InvestigationHumblet-Baron S, Sather B, Anover S, Becker-Herman S, Kasprowicz DJ, Khim S, Nguyen T, Hudkins-Loya K, Alpers CE, Ziegler SF, Ochs H, Torgerson T, Campbell DJ, Rawlings DJ -
Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin.
Journal of ImmunologyOmori M, Ziegler SF -
Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB.
PNAS USALee HC, Ziegler SF -
TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation.
Annual Review of ImmunologyLiu YJ, Soumelis V, Watanabe N, Ito T, Wang YH, Malefyt Rde W, Omori M, Zhou B, Ziegler SF -
FOXP3: not just for regulatory T cells anymore.
European Journal of ImmunologyZiegler SF -
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor.
Journal of ImmunologyLopes JE, Torgerson TR, Schubert LA, Anover SD, Ocheltree EL, Ochs HD, Ziegler SF -
FOXP3 controls regulatory T cell function through cooperation with NFAT.
CellWu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A -
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
The Journal of Experimental MedicineLiu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA -
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function.
Nature ImmunologyZiegler SF, Liu YJ