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Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness.
Critical Care MedicineMikacenic C, Bhatraju P, Robinson-Cohen C, Kosamo S, Fohner AE, Dmyterko V, Long SA, Cerosaletti K, Calfee CS, Matthay MA, Walley KR, Russell JA, Christie JD, Meyer NJ, Christiani DC, Wurfel MM -
MAP2K2 Delays Recovery in Murine Models of Acute Lung Injury and Associates with ARDS Outcome.
American Journal of Respiratory Cell and Molecular BiologyGong KQ, Mikacenic C, Long ME, Frevert C, Birkland TP, Charron J, Gharib SA, Manicone AM -
Relationships Between Age, Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), and Mortality Among Critically Ill Adults: A Cohort Study.
ShockSathe NA, Bhatraju PK, Mikacenic C, Morrell ED, Mabrey FL, Liles WC, Wurfel MM -
Differences between Children and Adults with COVID-19: It's Right under Our Nose.
American Journal of Respiratory Cell and Molecular BiologyMorrell ED, Mikacenic C -
Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019.
Critical Care ExplorationsMabrey FL, Morrell ED, Bhatraju PK, Sathe NA, Sakr SS, Sahi SK, West TE, Mikacenic C, Wurfel MM -
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations.
JCI InsightHelms L, Marchiano S, Stanaway IB, Hsiang TY, Juliar BA, Saini S, Zhao YT, Khanna A, Menon R, Alakwaa F, Mikacenic C, Morrell ED, Wurfel MM, Kretzler M, Harder JL, Murry CE, Himmelfarb J, Ruohola-Baker H, Bhatraju PK, Gale M Jr, Freedman BS -
The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.
Journal of ImmunologyAllenspach EJ, Shubin NJ, Cerosaletti K, Mikacenic C, Gorman JA, MacQuivey MA, Rosen ABI, Timms AE, Wray-Dutra MN, Niino K, Liggitt D, Wurfel MM, Buckner JH, Piliponsky AM, Rawlings DJ -
Clinical presentation, complications, and outcomes of hospitalized COVID-19 patients in an academic center with a centralized palliative care consult service.
Health Science ReportsBaker SM, Leedy DJ, Klafter JA, Zhang Y, Secrest KM, Osborn TR, Cheng RK, Judson SD, Merel SE, Mikacenic C, Bhatraju PK, Liles WC -
A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement.
American Journal of Respiratory and Critical Care MedicineShah FA, Meyer NJ, Angus DC, Awdish R, Azoulay É, Calfee CS, Clermont G, Gordon AC, Kwizera A, Leligdowicz A, Marshall JC, Mikacenic C, Sinha P, Venkatesh B, Wong HR, Zampieri FG, Yende S -
Comparison of host endothelial, epithelial and inflammatory response in ICU patients with and without COVID-19: a prospective observational cohort study.
Critical CareBhatraju PK, Morrell ED, Zelnick L, Sathe NA, Chai XY, Sakr SS, Sahi SK, Sader A, Lum DM, Liu T, Koetje N, Garay A, Barnes E, Lawson J, Cromer G, Bray MK, Pipavath S, Kestenbaum BR, Liles WC, Fink SL, West TE, Evans L, Mikacenic C, Wurfel MM -
Endotracheal aspirates contain a limited number of lower respiratory tract immune cells.
Critical CareOrlov M, Morrell ED, Dmyterko V, Hamerman JA, Wurfel MM, Mikacenic C -
Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome.
JCI InsightMorrell ED, Wiedeman A, Long SA, Gharib SA, West TE, Skerrett SJ, Wurfel MM, Mikacenic C -
A novel and rapid method to quantify Treg mediated suppression of CD4 T cells.
Journal of Immunological MethodsLong AE, Tatum M, Mikacenic C, Buckner JH -
Cutting edge: Genetic variation in TLR1 is associated with Pam3CSK4-induced effector T cell resistance to regulatory T cell suppression.
Journal of ImmunologyMikacenic C, Schneider A, Radella F, Buckner JH, Wurfel MM