Progress Against One Autoimmune Disease is Progress Against Them All

One in every 15 Americans suffers from an autoimmune diseasetype 1 diabetes, multiple sclerosis (MS), Crohn’s disease and rheumatoid arthritis are just a few. And because many causes of autoimmune diseases are shared, people living with an autoimmune disease are more likely to suffer from more than one of these destructive diseases. 

Benaroya Research Institute at Virginia Mason (BRI) is one of the few research institutes in the world dedicated to discovering causes and cures to eliminate autoimmune and immune system diseases. At BRI, our scientists aren’t focused on eliminating one or two autoimmune diseases—we’re taking on all 110+.

Because autoimmune diseases are connected, so is the way we’re fighting them. We're applying the breakthroughs we make against individual autoimmune diseases to make progress against them all. Through collaboration and cooperation between researchers, across clinical trials and with other institutions, we connect laboratory research to clinical trials and translate discoveries to real-life applications. As a world leader in scientific innovation, we’re leveraging this progress to eliminate autoimmune and immune system diseases in the future. 

Our discoveries are also having significant impact on people living with autoimmune and immune system diseases today—by improving the ability to predict disease risk, facilitate treatment, decrease progression of these diseases and make related therapies safer and more effective.

Our Collaborations with Other Scientists and Institutions Span the Globe

Immune Tolerance Network 

BRI leads the Immune Tolerance Network (ITN), a collaborative network for clinical research focused on the development of therapeutic approaches that lead to immune tolerance in asthma and allergy, autoimmune diseases such as type 1 diabetes, and solid organ transplantation. Learn more about the ITN or visit


BRI leads Type 1 Diabetes TrialNet, an international network that conducts clinical studies that evaluate new approaches to preventing, delaying and reversing the progression of type 1 diabetes. TrialNet is conducting clinical trials with researchers from 17 clinical centers in the United States and six internationally. An additional 200 affiliated research sites are participating in the TrialNet network. Learn more about TrialNet (fact sheet).

More Than 60 Years of Scientific Excellence

First established in 1956 as the Virginia Mason Research Center in Seattle, Washington, the nonprofit institute developed a unique niche as a basic sciences research institute associated with a major medical center and a teaching program. Renamed in 2002 in recognition of the Benaroya family of Seattle, BRI now houses more than 275 scientific and administrative staff with a research volume of more than $71 million a year, including grants from the National Institutes of Health, JDRF, The Leona M. and Harry B. Helmsley Charitable Trust and the National Multiple Sclerosis Society

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Research at BRI is conducted with the highest ethical standards and integrity. Our PDF icon Research Conflicts of Interest Policy is an important component of our research quality program. We also respect your privacy as detailed in this Joint Notice of Privacy Practices.