Recent Publications

The following list highlights BRI's 2021 publications. More selective listings of publications are also included on scientist biography pages. BRI Principal Investigators are listed in bold.

Altman MC, Calatroni A, Ramratnam S, Jackson DJ, Presnell S, Rosasco MG, Gergen PJ, Bacharier LB, O'Connor GT, Sandel MT, Kattan M, Wood RA, Visness CM, Gern JE; Inner City Asthma Consortium. Endotype of Allergic Asthma with Airway Obstruction in Urban Children. J Allergy Clin Immunol. 2021 Mar 10:S0091-6749(21)00373-0. doi: 10.1016/j.jaci.2021.02.040. Epub ahead of print. PMID: 33713771

Bolouri H, Speake C, Skibinski D, Long SA, Hocking AM, Campbell DJ, Hamerman JA, Malhotra U, Buckner JH; Benaroya Research Institute COVID-19 Research Team. The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity. J Clin Invest. 2021 Feb 1;131(3):e143648. doi: 10.1172/JCI143648. PMID: 33529167 | PMC7843226

Byrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Mellman I, Duffy D, Albert ML; Milieu Intérieur Consortium. Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers. J Exp Med. 2021 Jan 4;218(1):e20200606. doi: 10.1084/jem.20200606. PMID: 33175106 | PMC7664509

Calise J, Garabatos N, Bajzik V, Farrington M, Robinson D, Jeong D, Londei M, Wambre E. Optimal human pathogenic TH2 cell effector function requires local epithelial cytokine signaling. J Allergy Clin Immunol. 2021 Mar 1:S0091-6749(21)00282-7. doi: 10.1016/j.jaci.2021.02.019. Epub ahead of print. PMID: 33662368

Diggins KE, Serti E, Muir V, Rosasco M, Lu T, Balmas E, Nepom G, Long SA, Linsley PS. Exhausted-like CD8+ T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. JCI Insight. 2021 Feb 8;6(3):e142680. doi: 10.1172/jci.insight.142680. PMID: 33351781 | PMC7934874

Flatt AJS, Greenbaum CJ, Shaw JAM, Rickels MR. Pancreatic islet reserve in type 1 diabetes. Ann N Y Acad Sci. 2021 Feb 6. doi: 10.1111/nyas.14572. Epub ahead of print. PMID: 33550589

Frankel JK, Caumont F, DeBerg HA, Flores JP, Porter CR. Contemporary trends in management of stage 1 seminoma. Urol Oncol. 2021 Apr;39(4):240.e1-240.e8. doi: 10.1016/j.urolonc.2020.08.025. Epub 2021 Feb 16. PMID: 33602622

Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G; European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group. EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol. 2021 Mar 12. doi: 10.1111/pai.13496. Epub ahead of print. PMID: 33710678

Harten IA, Evanko SP, Choe CH, Lee EW, Patel BN, Bogdani M, Wight TN, Lee UJ. The extracellular matrix molecules versican and hyaluronan in urethral and vaginal tissues in stress urinary incontinence. Neurourol Urodyn. 2021 Mar;40(3):771-782. doi: 10.1002/nau.24635. Epub 2021 Mar 1. PMID: 33645869

Hirpara DH, O'Rourke C, Azin A, Quereshy FA, Wexner SD, Chadi SA. Impact of BMI on Adverse Events After Laparoscopic and Open Surgery for Rectal Cancer. J Gastrointest Cancer. 2021 Mar 3. doi: 10.1007/s12029-021-00612-2. Epub ahead of print. PMID: 33660225

Krawiec M, Fisher HR, Du Toit G, Bahnson HT, Lack G. Overview of oral tolerance induction for prevention of food allergy-Where are we now? Allergy. 2021 Feb 4. doi: 10.1111/all.14758. Epub ahead of print. PMID: 33539570

Lee HS, Chiorean MV, Boden E, Lord J, Irani S, Kozarek R, Larsen M, Ross A. Usefulness of Fluoroscopy for Endoscopic Balloon Dilation of Crohn's Disease-Related Strictures. Dig Dis Sci. 2021 Mar 19. doi: 10.1007/s10620-021-06935-1. Epub ahead of print. PMID: 33740171

Long SA, Speake C. Combination therapy in recent-onset type 1 diabetes. Lancet Diabetes Endocrinol. 2021 Apr;9(4):191-193. doi: 10.1016/S2213-8587(21)00044-9. Epub 2021 Mar 1. PMID: 33662335

Lu X, Chen X, Forney C, Donmez O, Miller D, Parameswaran S, Hong T, Huang Y, Pujato M, Cazares T, Miraldi ER, Ray JP, de Boer CG, Harley JB, Weirauch MT, Kottyan LC. Global discovery of lupus genetic risk variant allelic enhancer activity. Nat Commun. 2021 Mar 12;12(1):1611. doi: 10.1038/s41467-021-21854-5. PMID: 33712590 | PMC7955039

Malinczak CA, Parolia A, Fonseca W, Morris S, Rasky AJ, Bawa P, Zhang Y, Mire MM, Ziegler SF, Ptaschinski C, Chinnaiyan AM, Lukacs NW. TSLP-Driven Chromatin Remodeling and Trained Systemic Immunity after Neonatal Respiratory Viral Infection. J Immunol. 2021 Mar 15;206(6):1315-1328. doi: 10.4049/jimmunol.2001205. Epub 2021 Jan 29. PMID: 33514510

Nguyen H, Guyer P, Ettinger RA, James EA. Non-Genetically Encoded Epitopes Are Relevant Targets in Autoimmune Diabetes. Biomedicines. 2021 Feb 17;9(2):202. doi: 10.3390/biomedicines9020202. PMID: 33671312 | PMC7922826

Orlov M, Morrell ED, Dmyterko V, Hamerman JA, Wurfel MM, Mikacenic C. Endotracheal aspirates contain a limited number of lower respiratory tract immune cells. Crit Care. 2021 Jan 6;25(1):14. doi: 10.1186/s13054-020-03432-1. PMID: 33407749 | PMC7787413

Piganelli JD, Mamula MJ, James EA. The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes. Front Endocrinol (Lausanne). 2021 Feb 18;11:624590. doi: 10.3389/fendo.2020.624590. PMID: 33679609 | PMC7930070

Rinchai D, Roelands J, Toufiq M, Hendrickx W, Altman MC, Bedognetti D, Chaussabel D. BloodGen3Module: Blood transcriptional module repertoire analysis and visualization using R. Bioinformatics. 2021 Feb 24:btab121. doi: 10.1093/bioinformatics/btab121. Online ahead of print. PMID: 33624743

Rose LM, DeBerg HA, Vishnu P, Frankel JK, Manjunath AB, Flores JPE, Aboulafia DM. Incidence of Skin and Respiratory Immune-Related Adverse Events Correlates With Specific Tumor Types in Patients Treated With Checkpoint Inhibitors. Front Oncol. 2021 Jan 15;10:570752. doi: 10.3389/fonc.2020.570752. PMID: 33520695 | PMC7844139

Ruffner MA, Hu A, Dilollo J, Benocek K, Shows D, Gluck M, Spergel JM, Ziegler SF, Hill DA, Cerosaletti K. Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis. J Immunol. 2021 Mar 15;206(6):1361-1371. doi: 10.4049/jimmunol.2000973. Epub 2021 Feb 8. PMID: 33558373 | PMC7946729

Sims EK, Bundy BN, Stier K, Serti E, Lim N, Long SA, Geyer SM, Moran A, Greenbaum CJ, Evans-Molina C, Herold KC; Type 1 Diabetes TrialNet Study Group. Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Sci Transl Med. 2021 Mar 3;13(583):eabc8980. doi: 10.1126/scitranslmed.abc8980. PMID: 33658358

Song J, Schwenzer A, Wong A, Turcinov S, Rims C, Martinez LR, Arribas-Layton D, Gerstner C, Muir VS, Midwood KS, Malmström V, James EA, Buckner JH. Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis. JCI Insight. 2021 Mar 8;6(5):145217. doi: 10.1172/jci.insight.145217. PMID: 33507879

Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA. Evolution of epitope-specific IgE and IgG4 antibodies in children enrolled in the LEAP trial. J Allergy Clin Immunol. 2021 Feb 13:S0091-6749(21)00216-5. doi: 10.1016/j.jaci.2021.01.030. Epub ahead of print. PMID: 33592205

Wiedeman AE, Speake C, Long SA. The many faces of islet antigen-specific CD8 T cells: clues to clinical outcome in type 1 diabetes. Immunol Cell Biol. 2021 Jan 22. doi: 10.1111/imcb.12437. Epub ahead of print. PMID: 33483981