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Oct 2025
Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes
J Clin InvestGabriele Sassi, Pierre Lemaitre, Laia Fernández Calvo, Francesca Lodi, Álvaro Cortés Calabuig, Samal Bissenova, Amber Wouters, Laure Degroote, Marijke Viaene, Niels Vandamme, Lauren Higdon, Peter S Linsley, S Alice Long, Chantal Mathieu, Conny Gysemans -
Jul 2025
Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications.
Front ImmunolCheng Z, Wang LJ, Honaker Y, Cincotta SA, Page CE, Vollhardt S, Yuan V, Long SA, Xiao Y, Beilke JN, Arron JR, Bluestone JA -
Jun 2025
Longitudinally stable T cell function and innate immune activation distinguish healthy adult immunotypes.
Sci Transl MedSmithmyer ME, Hu A, Dufort MJ, Hocking AM, Wiedeman AE, Fasano KJ, Torgerson TR, Skene PJ, Reading J, Li X, Gong Q, Long SA, Lacy-Hulbert A, Gustafson CE, Buckner JH, Speake C, members of the BRI Sound Life Project Team, BRI Sound Life Project Team -
Jun 2025
Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes
Nat CommunAna Lledó-Delgado, Paula Preston-Hurlburt, Lauren Higdon, Alex Hu, Eddie James, Noha Lim, S Alice Long, James McNamara, Hai Nguyen, Elisavet Serti, Tomokazu S Sumida, Kevan C Herold -
Mar 2025
Emerging Concepts and Success Stories in Type 1 Diabetes Research: A Road Map for a Bright Future.
DiabetesMallone R, Sims E, Achenbach P, Mathieu C, Pugliese A, Atkinson M, Dutta S, Evans-Molina C, Klatzmann D, Koralova A, Long SA, Overbergh L, Rodriguez-Calvo T, Ziegler AG, You S -
Oct 2024
42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque.
bioRxivMakatsa MS, Kus A, Wiedeman A, Long SA, Seshadri C -
Aug 2024
Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at-risk for type 1 diabetes.
J Clin InvestLledó-Delgado A, Preston-Hurlburt P, Currie S, Clark P, Linsley PS, Long SA, Liu C, Koroleva G, Martins AJ, Tsang JS, Herold KC -
Jul 2024
PD-L1 and PD-1 Are Associated with Clinical Outcomes and Alveolar Immune Cell Activation in ARDS.
Am J Respir Cell Mol BiolMorrell ED, Holton SE, Wiedeman A, Kosamo S, Mitchem MA, Dmyterko V, Franklin Z, Garay A, Stanaway IB, Liu T, Sathe NA, Mabrey FL, Stapleton RD, Malhotra U, Speake C, Hamerman JA, Pipavath S, Evans L, Bhatraju PK, Long SA, Wurfel MM, Mikacenic C -
Jun 2024
Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes.
Commun BiolWitkop EM, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk VH, Fuchs B, Long SA, Linsley PS -
May 2024
Integrating Omics into Functional Biomarkers of Type 1 Diabetes.
Cold Spring Harb Perspect MedLong SA, Linsley PS -
May 2024
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.
Sci Transl MedBender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group -
May 2024
Impact on in-depth immunophenotyping of delay to peripheral blood processing.
Clin Exp ImmunolHigdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE -
May 2024
Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles.
Front ImmunolLong SA, Muir VS, Jones BE, Wall VZ, Ylescupidez A, Hocking AM, Pribitzer S, Thorpe J, Fuchs B, Wiedeman AE, Tatum M, Lambert K, Uchtenhagen H, Speake C, Ng B, Heubeck AT, Torgerson TR, Savage AK, Maldonado MA, Ray N, Khaychuk V, Liu J, Linsley PS, Buckner JH -
Apr 2024
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review.
Commun Med (Lond)Felton JL, Redondo MJ, Oram RA, Speake C, Long SA, Onengut-Gumuscu S, Rich SS, Monaco GSF, Harris-Kawano A, Perez D, Saeed Z, Hoag B, Jain R, Evans-Molina C, DiMeglio LA, Ismail HM, Dabelea D, Johnson RK, Urazbayeva M, Wentworth JM, Griffin KJ, Sims EK, ADA/EASD PMDI -
Oct 2023
Th2 cell clonal expansion at diagnosis in human type 1 diabetes.
Clin ImmunolNarsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD
