TrialNet Pathway to Prevention Study

Get Screened for T1D Risk

The first step in joining our study is to visit the TrialNet Screening page.

Study Name: TrialNet Pathway to Prevention Study
Principal Investigator: Carla Greenbaum, MD
Phone: 1-800-888-4187
Email: Diabetes@BenaroyaResearch.org

TrialNet Diabetes Risk Screening is available and free to eligible family members of people with type 1 diabetes through an international research effort and BRI. Visit our screening page to start.

What is the TrialNet Pathway to Prevention Study?

TrialNet is screening relatives of people with type 1 diabetes to find out if these family members are at risk for developing diabetes. Relatives of people with type 1 diabetes have about a three to four percent chance of testing positive for autoantibodies associated with diabetes. If you learn you are at risk for developing type 1 diabetes, additional tests will be offered to estimate your chances of developing type 1 diabetes. If you qualify, you may have an opportunity to enroll in a prevention trial. All research volunteers will be closely monitored for early detection of type 1 diabetes. Early detection of type 1 diabetes may improve your blood sugar control and reduce your chances of developing complications. You will be part of a research program that may help other people at risk for type 1 diabetes.

Who can participate?

  • Individuals who are 1-45 years of age with a parent, child, brother or sister with type 1 diabetes
  • Individual who are 1-20 years of age with a niece, nephew, aunt, uncle, grandparent, half-sibling or cousin with type 1 diabetes

Note: A relative diagnosed before the age of 40 AND started on insulin within the first year of diagnosis may have type 1 diabetes.

What will study participants be asked to do?

Screening involves a simple blood test for the presence of diabetes-related autoantibodies that may appear years before type 1 diabetes symptoms develop. TrialNet has established screening sites throughout North America. Please email or call us at 1 (800) 888-4187 to find a screening location near you or to a request a test kit.

Based on the results of your Pathway to Prevention screening, you may be eligible to join a prevention trial: Abatacept